macrophage

Debris-eating immune cell

A macrophage is a large white blood cell that engulfs and digests cellular debris, pathogens, and foreign substances—a process called phagocytosis.

Macrophages are part of the immune system's first line of defense, patrolling tissues to detect and destroy invaders.

They also help initiate immune responses by presenting antigens to other immune cells.

phagocytosis

engulf

Completely surround and cover

receptor · scavenger · digestion · pathogen · apoptotic · endocytosis · exocytosis · vesicle · degradation · particle

signaling

cytokine

Immune signaling molecule

receptor · secretion · cascade · mediator · release · production

disease

granuloma

Inflammatory mass walling off foreign material

fibrosis · autoimmunity · sepsis · chronic inflammation · tumor · metastasis · HIV · leishmaniasis · rheumatoid · infection

types

monocyte

Phagocytic blood leukocyte

peritoneal · splenic · bone marrow · circulating · infiltrating · differentiation · precursor · hematopoiesis

immunity

innate

Existing since birth

complement · antibody · inflammation · defense · pathogen · immune response · surveillance · recognition · immunology · tolerance

polarization

M2

Broad money supply measure

anti-inflammatory · activation · plasticity · phenotype · reprogramming · regulatory · spectrum · functional · heterogeneity

Categories
Opposites
immune cell function

macrophagelymphocyte

Immune system white cell

B cell · T cell · antibody · natural killer cell · mast cell

cellular role in tissue

macrophagefibroblast

Fiber-producing connective cell

stem cell · hepatocyte · neuron · osteoblast

cellular role in phagocytosis

macrophagepathogen

Disease-causing microorganism

bacterium · debris · foreign body

Family

macrophages

Familiarity
Top 500,000
Profile
Used worldwide · Timeless · Concrete · Rated G