granuloma
Walled-off tissue inflammation
A granuloma is a small mass of inflamed tissue, typically formed when the immune system walls off substances it perceives as foreign but cannot eliminate.
Granulomas appear in conditions like tuberculosis, sarcoidosis, and Crohn's disease, and can form around splinters or other foreign bodies: The biopsy revealed granulomas consistent with fungal infection.
Rounded small lump
- lesionArea of pathological change
- massQuantity of matter
- lumpShapeless solid mass
- swellingAbnormal tissue enlargement
rounded · firm · discrete · palpable · visible · raised · localized · cluster
Localized cell death
- fibrosisPathological connective tissue buildup
- biopsyTissue sample for diagnosis
- stainingApplying dye or pigment
- microscopyTechnique using powerful lenses
tissue · specimen · central · surrounding · rim · architecture · pattern
Mycobacterial lung disease
- sarcoidosisGranulomatous inflammatory disorder
- leprosyMycobacterial infection causing disfigurement
- histoplasmosisSpore-caused pulmonary mycosis
- Crohn'sChronic intestinal inflammation disorder
Immune signaling proteins
- T-cellsThymus-matured immune lymphocytes
- interferonImmune response protein
- antigenImmune response inducer
- lymphocytesAdaptive immunity cells
monocytes · dendritic · inflammatory · response · activation · recruitment · barrier · defense
Engulfing immune cell
- multinucleatedHaving several nuclei
- aggregationCombined collection of items
- coalesceUnite into one mass
- walled-offEnclosed by barriers
organized · circumscribed · discrete · focal · collection · clustering · encapsulation
nodule
Rounded small lump
swelling · rounded · firm · discrete · palpable · visible · raised · localized · cluster · solitary
necrosis
Localized cell death
- fibrosisPathological connective tissue buildup
- biopsyTissue sample for diagnosis
- stainingApplying dye or pigment
microscopy · tissue · specimen · central · surrounding · rim · architecture · pattern
tuberculosis
Mycobacterial lung disease
- sarcoidosisGranulomatous inflammatory disorder
- leprosyMycobacterial infection causing disfigurement
- histoplasmosisSpore-caused pulmonary mycosis
Crohn's · silicosis · fungal · parasitic · reaction · irritant
cytokines
Immune signaling proteins
- T-cellsThymus-matured immune lymphocytes
- interferonImmune response protein
- antigenImmune response inducer
lymphocytes · monocytes · dendritic · inflammatory · response · activation · recruitment · barrier · defense · chronic
macrophage
Engulfing immune cell
- multinucleatedHaving several nuclei
- aggregationCombined collection of items
- coalesceUnite into one mass
walled-off · organized · circumscribed · discrete · focal · collection · clustering · encapsulation
granulomaneoplasm
Abnormal tissue mass
tumor · malignancy · malignant tumor · carcinoma · sarcoma