sarcoidosis
Systemic granulomatous condition
Sarcoidosis is a disease in which clusters of inflammatory cells called granulomas form in various organs, most commonly the lungs and lymph nodes.
The cause is unknown.
Symptoms range from mild to severe and may include fatigue, shortness of breath, and skin lesions.
Many cases resolve without treatment; others become chronic: She was diagnosed with sarcoidosis after a routine chest X-ray.
Body's outer layer
- eyesOrgans of sight
- uveitisUveal layer inflammation
- heartCirculatory system's pump
- liverAbdominal detoxifying organ
spleen · lymph nodes · nervous system · kidneys · joints · parotid · erythema nodosum · cardiac
Respiratory chest organs
- fibrosisPathological connective tissue buildup
- interstitialRelating to small gaps
- dyspneaLabored respiration condition
- coughExplosive airway clearing
chest · bilateral · bronchial · alveoli · respiratory · spirometry · pulmonology · chest x-ray
Having several nuclei
- nodulesSmall rounded protuberances
- lesionsAreas of damaged tissue
- biopsyTissue sample for diagnosis
- histologyStudy of tissue structure
pathology · tissue · formation · clusters · microscopic · inflammatory · fibrotic · calcified
Inflammation-suppressing steroid medications
- prednisoneSynthetic corticosteroid medication
- methotrexateAntifolate chemotherapy agent
- hydroxychloroquineAntimalarial and immunosuppressant drug
- immunosuppressantsDrugs reducing body defenses
remission · flare-ups · monitoring · tapering · maintenance · refractory · observation · watchful waiting
Thymus-matured immune lymphocytes
- granulomatousForming inflammatory tissue masses
- lymphocytesAdaptive immunity cells
- macrophagesLarge pathogen-engulfing immune cells
- cytokinesImmune signaling proteins
interleukin · CD4 · immune response · antigens · ACE · immunopathology · activated · dysregulation
Tissue sample for diagnosis
- chest x-rayRadiographic image of torso
- CT scanTomographic diagnostic imaging
- pulmonary functionLung operational status
- bronchoscopyInternal lung inspection via tube
PET scan · differential · exclusion · histological · staging
Continuing despite difficulty
- progressiveFavoring reform and innovation
- relapsingReturning to worse state
- lifelongLasting entire existence
- managementOrganizing and directing resources
debilitating · remission · flare-ups · monitoring · long-term · incurable · indolent · prognosis
skin
Body's outer layer
liver · spleen · lymph nodes · nervous system · kidneys · joints · parotid · erythema nodosum · cardiac · hypercalcemia
lungs
Respiratory chest organs
- fibrosisPathological connective tissue buildup
- interstitialRelating to small gaps
- dyspneaLabored respiration condition
cough · chest · bilateral · bronchial · alveoli · respiratory · spirometry · pulmonology · chest x-ray · CT scan
multinucleated
Having several nuclei
histology · pathology · tissue · formation · clusters · microscopic · inflammatory · fibrotic · calcified · necrosis
corticosteroids
Inflammation-suppressing steroid medications
- prednisoneSynthetic corticosteroid medication
- methotrexateAntifolate chemotherapy agent
- hydroxychloroquineAntimalarial and immunosuppressant drug
immunosuppressants · remission · flare-ups · monitoring · tapering · maintenance · refractory · observation · watchful waiting · relapse
T-cells
Thymus-matured immune lymphocytes
- granulomatousForming inflammatory tissue masses
- lymphocytesAdaptive immunity cells
- macrophagesLarge pathogen-engulfing immune cells
cytokines · interleukin · CD4 · immune response · antigens · ACE · immunopathology · activated · dysregulation
biopsy
Tissue sample for diagnosis
- chest x-rayRadiographic image of torso
- CT scanTomographic diagnostic imaging
- pulmonary functionLung operational status
bronchoscopy · PET scan · differential · exclusion · histological · staging
persistent
Continuing despite difficulty
- progressiveFavoring reform and innovation
- relapsingReturning to worse state
- lifelongLasting entire existence
management · debilitating · remission · flare-ups · monitoring · long-term · incurable · indolent · prognosis · quality of life
- diseasescancer, diabetes, tuberculosis, influenza, measles
- Lungslungs, lung, bronchi, bronchus, alveoli
- Respiratory Problemsasthma, bronchitis, pneumonia, COPD, emphysema
- Chest Conditionspneumonia, bronchitis, asthma, emphysema, lung cancer
- Lung Conditionsasthma, bronchitis, COPD, emphysema, pneumonia
- lung diseasespneumonia, pneumoconiosis, bronchitis, silicosis, emphysema
sarcoidosistuberculosis
Mycobacterial lung disease
histoplasmosis · Crohn's disease · leprosy · fungal infection