fibroblast
Connective tissue cell
A fibroblast is a cell that produces collagen and other fibers forming the structural framework of connective tissue.
Fibroblasts are essential to wound healing, generating the scar tissue that closes injuries.
They appear throughout the body in skin, tendons, and organs, maintaining the matrix that holds tissues together.
Living tissue under epidermis
- stromaSupportive tissue framework
- fasciaConnective tissue sheet
- tendonsFibrous connective cords
- ligamentsTough tissue joining bones
adipose · cartilage · cornea · gingiva · pulp · interstitial · areolar · reticular
Overgrown scar tissue
- cirrhosisIrreversible hepatic scarring
- sclerodermaSkin-tightening autoimmune condition
- desmoplasiaFibrous tissue proliferation around neoplasms
- contracturePermanent tissue shortening
adhesions · aberrant · dysregulated · activated · senescent
Gel surrounding the nucleus
- nucleusCentral controlling part
- membraneThin tissue sheet
- mitochondriaCell's energy-producing organelles
- endoplasmic reticulumCytoplasmic membrane network for synthesis
cytoskeleton · ribosome · lysosome · proliferation · differentiation · migration · adhesion · spindle-shaped
Combining parts into whole
- secretionSubstance released by glands
- elastinProtein enabling tissue recoil
- triple helixThree-strand molecular spiral
- amino acidsOrganic compounds forming proteins
crosslinking · deposition · assembly · glycoproteins · production · bundling · maturation · turnover
Coiled, or an injury
- repairRestore to working order
- granulationMaking into small grains
- contractionReduction in size
- scarPermanent mark from healing
regeneration · remodeling · closure · migration · growth factors · debridement · hemostasis · maturation
Temporary elevated work structure
- hydrogelWater-swollen polymer structure
- biomaterialSubstance for biological integration
- bioprintingDepositing living cells mechanically
- skin graftTransplanted tissue covering wounds
cell culture · passage · immortalized · seeding · expansion · bioreactor · autologous
dermis
Living tissue under epidermis
ligaments · adipose · cartilage · cornea · gingiva · pulp · interstitial · areolar · reticular · papillary
keloid
Overgrown scar tissue
- cirrhosisIrreversible hepatic scarring
- sclerodermaSkin-tightening autoimmune condition
- desmoplasiaFibrous tissue proliferation around neoplasms
contracture · adhesions · aberrant · dysregulated · activated · senescent
cytoplasm
Gel surrounding the nucleus
- nucleusCentral controlling part
- membraneThin tissue sheet
- mitochondriaCell's energy-producing organelles
endoplasmic reticulum · cytoskeleton · ribosome · lysosome · proliferation · differentiation · migration · adhesion · spindle-shaped · morphology
synthesis
Combining parts into whole
- secretionSubstance released by glands
- elastinProtein enabling tissue recoil
- triple helixThree-strand molecular spiral
amino acids · crosslinking · deposition · assembly · glycoproteins · production · bundling · maturation · turnover
wound
Coiled, or an injury
- repairRestore to working order
- granulationMaking into small grains
- contractionReduction in size
scar · regeneration · remodeling · closure · migration · growth factors · debridement · hemostasis · maturation · keloid
scaffold
Temporary elevated work structure
- hydrogelWater-swollen polymer structure
- biomaterialSubstance for biological integration
- bioprintingDepositing living cells mechanically
skin graft · cell culture · passage · immortalized · seeding · expansion · bioreactor · autologous
fibroblastleukocyte
Infection-fighting blood cell
immune cell · white blood cell · macrophage · lymphocyte · neutrophil