mast cell
Allergy response cell
A mast cell is a type of immune cell found in connective tissue throughout the body, particularly near blood vessels, nerves, and surfaces exposed to the environment like skin and mucous membranes.
Mast cells store granules containing histamine and other inflammatory chemicals, releasing them when triggered by allergens or injury.
This release causes the symptoms of allergic reactions—swelling, itching, redness.
Mast cell activation can trigger anaphylaxis in severe cases.
Allergy-response compound
- allergenImmune response trigger
- sensitizationIncreased responsiveness to stimuli
- hypersensitivityExaggerated response to stimuli
- atopyHereditary hypersensitivity to allergens
hay fever · asthma · eczema · rhinitis · urticaria · hives · pruritus · wheezing
Allergy-response compound
- heparinSubstance preventing coagulation
- prostaglandinsLipid-derived signaling compounds
- cytokinesImmune signaling proteins
- granulesSmall discrete particles
serotonin · proteases · interleukins · bronchoconstriction · vasodilation · edema · flushing · preformed
Adrenal stress hormone
- shockViolent sudden disturbance
- angioedemaSudden deep tissue swelling
- bronchospasmInvoluntary narrowing of airways
- hypotensionAbnormally reduced arterial pressure
vasodilation · urticaria · airway obstruction · stridor · tachycardia · EpiPen · emergency · mast cell activation
Small discrete particles
- connective tissueSupportive biological matrix
- mucosalOf moist body linings
- bone marrowBlood cell birthplace
- precursorSomething that comes first
maturation · skin · gut · lung · heterogeneity · lifespan · Paul Ehrlich
Rapid increase in quantity
- bone marrowBlood cell birthplace
- skin lesionsDamaged areas of dermis
- gastrointestinalRelating to digestive tract
- flushingWashing by water surge
Inherited pathogen defense system
- pathogenDisease-causing microorganism
- antimicrobialKills or inhibits germs
- wound healingRestoration after injury
- phagocytosisCellular ingestion of particles
histamine
Allergy-response compound
- allergenImmune response trigger
- sensitizationIncreased responsiveness to stimuli
- hypersensitivityExaggerated response to stimuli
atopy · hay fever · asthma · eczema · rhinitis · urticaria · hives · pruritus · wheezing · allergic
histamine
Allergy-response compound
- heparinSubstance preventing coagulation
- prostaglandinsLipid-derived signaling compounds
- cytokinesImmune signaling proteins
granules · serotonin · proteases · interleukins · bronchoconstriction · vasodilation · edema · flushing · preformed
epinephrine
Adrenal stress hormone
- shockViolent sudden disturbance
- angioedemaSudden deep tissue swelling
- bronchospasmInvoluntary narrowing of airways
hypotension · vasodilation · urticaria · airway obstruction · stridor · tachycardia · EpiPen · emergency · mast cell activation · adrenaline
granules
Small discrete particles
- connective tissueSupportive biological matrix
- mucosalOf moist body linings
- bone marrowBlood cell birthplace
precursor · maturation · skin · gut · lung · heterogeneity · lifespan · Paul Ehrlich
proliferation
Rapid increase in quantity
- bone marrowBlood cell birthplace
- skin lesionsDamaged areas of dermis
- gastrointestinalRelating to digestive tract
innate immunity
Inherited pathogen defense system
- pathogenDisease-causing microorganism
- antimicrobialKills or inhibits germs
- wound healingRestoration after injury
- immune cellsT cells, lymphocytes, macrophage, macrophages, monocyte
- cellscells, blood cell, cell theory, nerve cell, red blood cell
- immunityimmune, immunity, immune system, immune response, immune cells
- blood cellsred blood cell, red blood cells, white blood cell, white blood cells, red cells
- skin anatomydermis, epidermis, hypodermis, subcutis, cutis
- histologyhistology, tissue, cells, microscope slides, tissue sections