prostaglandins

Fatty acid messengers

Prostaglandins are hormone-like compounds produced throughout the body that regulate numerous physiological processes—inflammation, blood flow, blood clotting, and the contraction of smooth muscle.

They play key roles in fever, pain response, and childbirth.

Anti-inflammatory drugs like aspirin and ibuprofen work partly by blocking prostaglandin synthesis.

reproduction

uterus

Female reproductive organ

cervix · dilation · induction · menstruation · dysmenorrhea · ovulation · implantation · parturition · oxytocin · effacement

inflammation

swelling

Abnormal tissue enlargement

fever · edema · cytokines · COX-2 · NSAIDs · ibuprofen · aspirin · histamine · anti-inflammatory · naproxen

biochemistry

phospholipids

Lipids with phosphate groups

omega-6 · polyunsaturated · receptors · signaling · metabolites

cardiovascular

vasodilation

Relaxation of vessel walls

circulation · hypertension · atherosclerosis

pain

sensitization

Increased responsiveness to stimuli

dysmenorrhea · tenderness · cramping · soreness · throbbing · chronic · acute · neuralgia

healing

angiogenesis

Formation of new vessels

remodeling · scarring · platelets · clotting

gastric

mucosa

Moist organ lining

duodenum · erosion

Categories
Opposites
signaling range/mechanism

prostaglandinsinsulin

Pancreatic glucose-regulating hormone

thyroxine · cortisol · estrogen · testosterone · growth hormone

inflammatory role

prostaglandinsglucocorticoids

Adrenal cortex steroid hormones

corticosteroids · NSAIDs · aspirin

Family

prostaglandin

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Used worldwide · Timeless · Rated G