prostaglandin
Inflammatory signaling molecule
Prostaglandins are hormone-like compounds produced throughout the body that regulate inflammation, pain, blood flow, and other physiological processes.
They play roles in fever, muscle contraction, and protecting the stomach lining.
Anti-inflammatory drugs like aspirin and ibuprofen work by blocking prostaglandin production: Prostaglandins released at the injury site triggered swelling and pain.
Abnormal tissue enlargement
- rednessCrimson-hued state
- feverElevated body temperature
- edemaPathological tissue puffiness
- painBodily or emotional distress
NSAIDs · ibuprofen · aspirin · naproxen · cytokines · histamine · acute · chronic
Relaxation of vessel walls
- vasoconstrictionArterial walls contracting inward
- blood flowMovement through vessels
- endotheliumCells lining blood vessels
- smooth muscleInvoluntary contractile tissue
blood pressure · circulation · arterial · capillary · perfusion · ischemia · hypotension
Female reproductive organ
- laborStrenuous effort; also childbirth
- childbirthInfant's emergence from womb
- contractionReduction in size
- cervixUterine opening to vagina
dilation · effacement · induction · oxytocin · parturition · menstruation · dysmenorrhea · ovulation
Pain-relieving medication
- NSAIDsOver-the-counter pain class
- ibuprofenAnti-inflammatory pain reliever
- aspirinAcetylsalicylic acid tablet
- acetaminophenCommon over-the-counter analgesic
naproxen · sensitization · migraine · headache · arthritis · cramping · dysmenorrhea · soreness
Signal-receiving molecule
- biosynthesisLiving production of molecules
- COX-2Inducible prostaglandin synthase
- cell membraneOuter layer of cytoplasm
- phospholipidPhosphate-containing membrane lipid
Coiled, or an injury
- tissue repairBiological wound healing process
- regenerationBiological self-repair process
- inflammationProtective tissue response
- fibroblastsCollagen-producing connective tissue cells
collagen · granulation · angiogenesis · remodeling · scar · growth factors · recovery · ulcer
swelling
Abnormal tissue enlargement
pain · NSAIDs · ibuprofen · aspirin · naproxen · cytokines · histamine · acute · chronic · arthritis
vasodilation
Relaxation of vessel walls
- vasoconstrictionArterial walls contracting inward
- blood flowMovement through vessels
- endotheliumCells lining blood vessels
smooth muscle · blood pressure · circulation · arterial · capillary · perfusion · ischemia · hypotension
uterus
Female reproductive organ
- laborStrenuous effort; also childbirth
- childbirthInfant's emergence from womb
- contractionReduction in size
cervix · dilation · effacement · induction · oxytocin · parturition · menstruation · dysmenorrhea · ovulation · implantation
analgesic
Pain-relieving medication
- NSAIDsOver-the-counter pain class
- ibuprofenAnti-inflammatory pain reliever
- aspirinAcetylsalicylic acid tablet
acetaminophen · naproxen · sensitization · migraine · headache · arthritis · cramping · dysmenorrhea · soreness · tenderness
receptor
Signal-receiving molecule
- biosynthesisLiving production of molecules
- COX-2Inducible prostaglandin synthase
- cell membraneOuter layer of cytoplasm
phospholipid · omega-6 · bioactive · cascade · pathway
wound
Coiled, or an injury
- tissue repairBiological wound healing process
- regenerationBiological self-repair process
- inflammationProtective tissue response
fibroblasts · collagen · granulation · angiogenesis · remodeling · scar · growth factors · recovery · ulcer
- Biochemicalsamino acid, amino acids, protein, proteins, DNA
- secretionssaliva, sweat, mucus, bile, tears
- Lipid Mediatorsendocannabinoids, endocannabinoid
- obstetric drugsoxytocin, epidural, fentanyl, progesterone, prenatal vitamins
- signaling moleculeshormones, neurotransmitters, histamine, growth factors, cytokines
- cell signalingreceptor, ligand, receptors, signaling, kinase
prostaglandinsteroid hormone
Cholesterol-based bodily regulator
corticosteroid · insulin · thyroxine · adrenaline · growth hormone
prostaglandinanti-inflammatory
Inflammation-reducing agent
cortisol · corticosteroid · COX inhibitor · NSAID · aspirin