fibroblasts
Matrix-making tissue cells
Fibroblasts are cells that produce collagen and other fibers forming the structural framework of connective tissue.
They're essential for wound healing, generating the scar tissue that closes injuries.
In laboratory research, fibroblasts are commonly cultured because they grow readily and survive well outside the body.
The fibroblasts migrated to the wound site within hours.
Rapid increase in quantity
- differentiationRecognizing meaningful differences
- adhesionState of clinging fast
- migrationMovement to new territory
- secretionSubstance released by glands
cytokines · growth factors · chemotaxis · remodeling · contraction
Structural body protein
- elastinProtein enabling tissue recoil
- connective tissueSupportive biological matrix
- dermisLiving tissue under epidermis
- stromaSupportive tissue framework
cytoplasm · nucleus · mitochondria · endoplasmic reticulum · Golgi apparatus · cytoskeleton · actin · cell membrane
Restoration after injury
- scar formationFibrous tissue replacing damaged skin
- tissue repairBiological wound healing process
- contracturePermanent tissue shortening
- inflammationProtective tissue response
angiogenesis · tensile strength · debridement · hemostasis · maturation · scarring · keloid · closure
Permanent mark formation
- keloidOvergrown scar tissue
- sclerodermaSkin-tightening autoimmune condition
- cirrhosisIrreversible hepatic scarring
- desmoplasiaFibrous tissue proliferation around neoplasms
proliferation
Rapid increase in quantity
- differentiationRecognizing meaningful differences
- adhesionState of clinging fast
- migrationMovement to new territory
secretion · cytokines · growth factors · chemotaxis · remodeling · contraction
collagen
Structural body protein
- elastinProtein enabling tissue recoil
- connective tissueSupportive biological matrix
- dermisLiving tissue under epidermis
stroma · cytoplasm · nucleus · mitochondria · endoplasmic reticulum · Golgi apparatus · cytoskeleton · actin · cell membrane · organelles
wound healing
Restoration after injury
- scar formationFibrous tissue replacing damaged skin
- tissue repairBiological wound healing process
- contracturePermanent tissue shortening
inflammation · angiogenesis · tensile strength · debridement · hemostasis · maturation · scarring · keloid · closure · regeneration
scarring
Permanent mark formation
- keloidOvergrown scar tissue
- sclerodermaSkin-tightening autoimmune condition
- cirrhosisIrreversible hepatic scarring
- cellscells, blood cell, cell theory, nerve cell, red blood cell
- skinepidermis, dermis, skin, cutis, pores
- biological materialstissue, blood, plasma, serum, bone marrow
- skin anatomydermis, epidermis, hypodermis, subcutis, cutis
- wound healingscab, scar, granulation, wound closure, scar formation
- connective tissueconnective tissue, collagen, elastin, cartilage, tendon
fibroblastsneurons
Signal-transmitting brain cells
adipocytes · lymphocytes · macrophages · red blood cells · photoreceptors