epigenetics

Beyond the code

Epigenetics is the study of how gene expression changes without altering the underlying DNA sequence.

Environmental factors, behaviors, and experiences can switch genes on or off, and some of these changes pass to offspring.

The field explains why identical twins diverge over time, or how trauma might affect subsequent generations: Epigenetics shows that nurture can reshape nature.

molecular

chromatin

Nuclear protein-wrapped genetic material

DNMT · HAT · HDAC · enhancer · promoter · insulator

mechanisms

methylation

Attaching a methyl group

writers · erasers · readers · CpG islands · bookmarking

inheritance

transgenerational

Crossing age cohorts

paternal · germline · intergenerational · Lamarckian · reprogramming · inheritance patterns · erasure · resetting

environmental

diet

Customary food consumption

smoking · alcohol · nutrition · exercise · lifestyle · exposure · heavy metals · pesticides · BPA · adversity

expression

transcription

Written version of speech

upregulation · downregulation · allele · dosage compensation

disease

cancer

Uncontrolled cell proliferation disease

tumor suppressor · biomarkers · aging · neurodegeneration · metabolic disorders · autoimmune

research

canalization

Directing into fixed courses

Categories
Opposites
mechanism of inheritance

epigeneticsgenetic determinism

Heredity alone shapes traits

genetic mutation · point mutation · genetics · mutation · genomics

Family

epigenetic

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