histone

Chromatin's protein core

Histones are proteins found in the nuclei of cells that act as spools around which DNA winds itself.

This packaging allows the extremely long strands of genetic material to fit compactly inside the cell while remaining accessible for reading and copying.

Histones also play a crucial role in gene regulation; chemical modifications to these proteins can turn genes on or off without changing the DNA sequence itself.

epigenetics

methylation

Attaching a methyl group

erasers · readers · imprinting · bivalent · marks · inheritance

structure

lysine

Essential amino acid

conserved

nucleosome

linker

Combiner of separate parts

solenoid · nucleation · positioning · dyad

chromatin

accessibility

Ease of approach

variants

canonical

Accepted as standard

enzymes

HAT

Multi-field technical acronym

  • HDACChromatin-compacting enzyme
  • kinasePhosphate-transferring enzyme
Categories
Opposites
dna packaging components

histoneDNA

Hereditary code molecule

double helix · nucleic acid

Phrases
Family

histone deacetylase, histology

Familiarity
Top 1,000,000
Profile
Used worldwide · Timeless · Concrete · Rated G