DNMT
Adds methyl groups
DNMT stands for DNA methyltransferase, an enzyme that adds methyl groups to DNA molecules.
This chemical modification typically silences genes without altering the underlying genetic sequence—a key mechanism in epigenetics.
DNMTs play essential roles in development, cell differentiation, and gene regulation: DNMT inhibitors are being studied as cancer treatments.
- Epigeneticsepigenetics, histone, nucleosome, methylation, acetylation
- Methylation5-methylcytosine, CpG islands, S-adenosylmethionine
- MethyltransferasesMGMT
- Chromatin Proteinshistones, chromatin, nucleosome, readers, writers