mast cell activation

Histamine release trigger

Mast cell activation is the process by which mast cells—immune cells found throughout body tissues—release histamine and other inflammatory chemicals in response to triggers.

This response is normal during allergic reactions and wound healing, but when dysregulated, causes chronic symptoms: flushing, hives, digestive problems, and in severe cases, anaphylaxis.

Her mast cell activation was triggered by stress and certain foods.

Opposites
physiological outcome

mast cell activationimmunosuppression

Reduced bodily defense activation

anergy · desensitization

Family

activate, activation, mast cell

Familiarity
Top 1,000,000
Profile
Used worldwide · Timeless · Rated G