biomarker

Health measurement molecule

A biomarker is a measurable biological indicator—a substance, structure, or process in the body that signals normal function, disease, or response to treatment.

Blood pressure, cholesterol levels, and tumor proteins are all biomarkers.

Doctors use them to diagnose conditions, track disease progression, and evaluate whether treatments are working: The biomarker showed the cancer responding to chemotherapy.

diagnostic

screening

Evaluative selection process

pathology · biopsy · imaging · differential · staging · monitoring · predictive · prognostic · sensitivity · specificity

molecular

protein

Folded amino chain

  • enzymeProtein that hastens reactions
  • metaboliteSubstance from cellular processes
  • antibodyProtein targeting foreign substances

receptor · lipid · carbohydrate · peptide · cytokine · hormone · antigen · nucleotide · RNA · DNA

detection

assay

Compositional evaluation procedure

microarray · electrophoresis · quantification · sensitivity · specificity · validation · high-throughput · nanoparticle · analyte · readout

clinical

troponin

Muscle regulatory protein complex

  • PSAFree civic advertisement
  • HbA1cGlucose-bound red cell protein
  • creatinineMuscular metabolism waste compound

cholesterol · glucose · hemoglobin · albumin · bilirubin · ferritin · cortisol · BNP · D-dimer · interleukin

genetic

mutation

Permanent DNA alteration

genome · chromosome · haplotype · variant · sequence · germline · somatic · epigenetic · microsatellite · translocation

health

prevention

Stopping something before occurring

cardiovascular · diabetes · obesity · metabolism · lifestyle · nutrition · longevity · baseline · intervention · wearable

Categories
Opposites
objectivity of measurement

biomarkersymptom

Indicator of disease

anecdotal evidence · patient history · feeling · sensation · lived experience

biological vs. clinical manifestation

biomarkersign

Mark conveying information

phenotype · syndrome

specificity of indication

biomarkervital sign

Measurable body function

Family

biomarkers

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