microarray
Spotted DNA grid
A microarray is a laboratory tool consisting of thousands of microscopic spots of DNA, proteins, or other molecules arranged in a grid on a solid surface.
Scientists use microarrays to measure the activity of many genes simultaneously or to detect specific biological molecules: The microarray revealed which genes were active in the tumor cells.
The technology revolutionized genomic research by enabling high-throughput analysis.
Small broken-off piece
- slideSmooth continuous movement
- glassTransparent solid from sand
- spottedSeen or patterned
- printedTransferred to paper
wells · platform · scanner · laser · fluorescence · hybridization · probe · spotting
Adjusting to a standard
- quantificationExpressing something numerically
- intensityStrength or force level
- backgroundOne's formative experiences
- noiseUnwanted auditory disturbance
spots · signal · threshold · clustering · heatmap · differential · statistical · bioinformatics
Hereditary code molecule
- RNAGene expression molecule
- cDNAReverse-transcribed genetic material
- genesUnits of heredity
- genomeOrganism's total hereditary material
expression · genotyping · alleles · polymorphism · mutation · nucleotide · chromosomes · loci
Facility for scientific investigation
- experimentationSystematic testing of ideas
- biotechnologyEngineering using living systems
- genomicsStudy of entire genetic sequences
- pharmacogenomicsGene-based drug response study
profiling · functional · pathway · biological · discovery · hypothesis · validation · replicates
Emotionally detached, medically precise
- screeningEvaluative selection process
- detectionAct of finding something
- diagnosisIdentification of illness
- prognosisPredicted disease course
oncology · pathology · patient · disease · biomarkers · classification · subtypes · predictive
chip
Small broken-off piece
printed · wells · platform · scanner · laser · fluorescence · hybridization · probe · spotting · gridding
normalization
Adjusting to a standard
- quantificationExpressing something numerically
- intensityStrength or force level
- backgroundOne's formative experiences
noise · spots · signal · threshold · clustering · heatmap · differential · statistical · bioinformatics · software
DNA
Hereditary code molecule
genome · expression · genotyping · alleles · polymorphism · mutation · nucleotide · chromosomes · loci · sequencing
laboratory
Facility for scientific investigation
- experimentationSystematic testing of ideas
- biotechnologyEngineering using living systems
- genomicsStudy of entire genetic sequences
pharmacogenomics · profiling · functional · pathway · biological · discovery · hypothesis · validation · replicates · controls
clinical
Emotionally detached, medically precise
- screeningEvaluative selection process
- detectionAct of finding something
- diagnosisIdentification of illness
prognosis · oncology · pathology · patient · disease · biomarkers · classification · subtypes · predictive · prognostic