pyruvate

Three-carbon metabolic molecule

Pyruvate is a molecule central to cellular metabolism—the end product of glycolysis, where glucose is broken down for energy.

From pyruvate, cells can generate ATP through aerobic respiration or, when oxygen is scarce, convert it to lactate.

Blood pyruvate levels and pyruvate dehydrogenase appear in biochemistry and medical contexts.

fermentation

lactate

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yeast · bacteria · brewing · wine · beer · sourdough · kimchi · acetaldehyde · carbon dioxide · muscle fatigue

metabolism

transamination

Amino group biochemical exchange

bioenergetics · cellular respiration · ATP · mitochondrion · enzymatic · intermediate · metabolite

dehydrogenase

decarboxylation

Carboxyl group elimination

mitochondria · carbon dioxide · E3 · irreversible · aerobic

gluconeogenesis

phosphoenolpyruvate

Glycolysis's penultimate metabolite

  • biotinB7, a metabolic cofactor
  • ATPCell's energy molecule
  • GTPGuanine nucleotide triphosphate

liver · kidney · fasting · Cori cycle · blood glucose · starvation

glycolysis

glucose

Primary cellular fuel

krebs

acetyl-CoA

Activated two-carbon metabolic intermediate

NADH · carbon dioxide · mitochondrial matrix · aerobic respiration

Categories
Opposites
metabolic pathway position

pyruvateglucose

Primary cellular fuel

phosphoenolpyruvate

metabolic fate/precursor

pyruvatelactate

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acetyl-CoA · alanine · ethanol · malate · citrate

Family

fermentation, decarboxylate

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