alpha-ketoglutarate
Citric cycle molecule
Alpha-ketoglutarate is a molecule central to cellular metabolism, serving as an intermediate in the Krebs cycle where cells generate energy.
It participates in amino acid synthesis and nitrogen transport.
As a supplement, it's marketed for athletic performance, muscle recovery, and anti-aging, though evidence for these claims remains limited: Some bodybuilders take alpha-ketoglutarate to boost endurance.
Tart organic compound
- mitochondriaCell's energy-producing organelles
- glutamateExcitatory neural transmitter
- NADHElectron-carrying coenzyme
- ATPCell's energy molecule
cellular respiration · pyruvate · acetyl-CoA · malate · energy production · aerobic · catabolism · biosynthesis
Amino group biochemical exchange
- glutamineEssential amino acid
- ammoniumCharged ammonia derivative
- liverAbdominal detoxifying organ
- deaminationAmino group removal process
Nuclear protein-wrapped genetic material
- gene expressionDNA to functional product
- cofactorEnzyme-activating compound
- hypoxiaInsufficient tissue oxygenation
- tumor suppressorGene preventing uncontrolled growth
Duration of existence
- anti-agingCounteracting effects of time
- athletic performancePhysical skill in sports
- muscle recoveryTissue rebuilding after strain
- bodybuildingMuscle enlargement for appearance
endurance · arginine · nitric oxide · vasodilation · pre-workout · dosage · bioavailability · oral
Mechanical blood filtration
- kidney diseaseImpaired renal function
- wound healingRestoration after injury
- burn treatmentCare for heat wounds
- surgical recoveryHealing after an operation
trauma · sepsis · parenteral · postoperative · ICU · muscle wasting · cachexia · therapeutic
citric acid
Tart organic compound
- mitochondriaCell's energy-producing organelles
- glutamateExcitatory neural transmitter
- NADHElectron-carrying coenzyme
ATP · cellular respiration · pyruvate · acetyl-CoA · malate · energy production · aerobic · catabolism · biosynthesis · intermediary
transamination
Amino group biochemical exchange
chromatin
Nuclear protein-wrapped genetic material
- gene expressionDNA to functional product
- cofactorEnzyme-activating compound
- hypoxiaInsufficient tissue oxygenation
longevity
Duration of existence
- anti-agingCounteracting effects of time
- athletic performancePhysical skill in sports
- muscle recoveryTissue rebuilding after strain
bodybuilding · endurance · arginine · nitric oxide · vasodilation · pre-workout · dosage · bioavailability · oral · capsule
dialysis
Mechanical blood filtration
- kidney diseaseImpaired renal function
- wound healingRestoration after injury
- burn treatmentCare for heat wounds
surgical recovery · trauma · sepsis · parenteral · postoperative · ICU · muscle wasting · cachexia · therapeutic
- Biochemicalsamino acid, amino acids, protein, proteins, DNA
- Metabolic Intermediatesshikimic acid, phosphoenolpyruvate, homocysteine, citrulline, pyruvate
- metabolitespyruvate, lactate, glucose, citrate, acetyl-CoA
- Cell BiochemicalsATP, ADP, NADH, FAD, acetyl-CoA
- keto acidspyruvate
- Krebs Cyclecitrate, succinyl-CoA, malate, acetyl-CoA, citric acid cycle
alpha-ketoglutaratecitrate
Salt of citrus acid
acetyl-CoA · pyruvate · malate · succinyl-CoA