transamination

Nitrogen group transfer

Transamination is a biochemical reaction in which an amino group transfers from one molecule to another, typically from an amino acid to a keto acid.

This process is central to protein metabolism, allowing the body to synthesize nonessential amino acids and break down others for energy.

Enzymes called transaminases or aminotransferases catalyze these reactions; elevated levels in blood tests often indicate liver damage.

aminoacids

glutamate

Excitatory neural transmitter

leucine · isoleucine · valine · phenylalanine · tyrosine · serine · threonine · lysine · arginine · histidine

enzymes

pyridoxal phosphate

Active coenzyme of B6

  • ALTLiver function indicator
  • coenzymeEnzyme's nonprotein helper molecule
  • cofactorEnzyme-activating compound

vitamin B6 · active site · serum levels

metabolism

energy production

Creating usable power supply

catabolism · mitochondria · cytosol

liver

hepatocyte

Functional liver cell

hepatitis · liver damage · biomarker · jaundice · liver disease · liver panel · clinical diagnosis

Opposites
nitrogen metabolism pathway type

transaminationdeamination

Amino group removal process

reductive amination · nitrogen fixation · amination

Family

transfers, ammonia, trans, amino, amine, transferase, transaminase

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