Cori cycle

Muscle-liver glucose exchange

The Cori cycle is the metabolic pathway in which lactate produced by muscles during anaerobic exercise travels to the liver, gets converted back to glucose, and returns to muscles for energy.

Named for biochemists Carl and Gerty Cori, it allows muscles to function when oxygen is limited: The Cori cycle helps clear lactic acid after a sprint.

mechanism

lactate

Produce milk naturally

  • liverAbdominal detoxifying organ
  • muscleContractile body tissue
  • pyruvateThree-carbon acid from glycolysis

glucose · hepatic · anaerobic · oxygen debt

physiology

muscle contraction

Fibers tensing and shortening

blood glucose · insulin · glucagon · homeostasis · glucose homeostasis · energy demand · sprint · ischemia · hypoxia · liver function

biochemistry

enzymes

Reaction-speeding proteins

cofactors · substrate

clinical

liver disease

Illness affecting blood-filtering organ

energetics

energy expenditure

Power used by activity

energy balance

Categories
Opposites
metabolic direction

Cori cycleglycolysis

Glucose metabolism producing ATP

aerobic respiration · citric acid cycle · beta-oxidation

metabolic state

Cori cyclelipogenesis

Metabolic fat production process

Family

cycle, metabolic, biochemical, glycolysis, metabolize, lactic acid

Familiarity
Top 2,000,000
Profile
Used worldwide · Timeless · Abstract · Rated G