copy number
Repeated sequence tally
Copy number refers to the quantity of a particular DNA sequence present in a genome or cell.
In genetics, it describes how many copies of a gene or segment exist: The gene has a copy number of two in most human cells.
Copy number variations—deletions or duplications of DNA segments—can affect disease risk and drug response.
In molecular biology, copy number also indicates how many copies of a plasmid or other genetic element a cell contains.
Increase in intensity
- deletionRemoval of content
- duplicationMaking an identical copy
- gainPositive return received
- lossBeing without something
segmental · polymorphism · submicroscopic · insertion · rearrangement · breakpoint · mosaic
Three chromosomes, not two
- karyotypeOrganized chromosome display
- chromosomal disorderIllness from atypical cellular genetics
- Down syndromeThird chromosome 21 present
- mosaicismMixed genetic makeup
Chromosome sequence visualization method
- microarrayGene expression detection tool
- Southern blotDNA transfer and detection method
- sequencingDetermining element order
- coverageExtent of inclusion
quantification · fluorescence · probe · hybridization · bioinformatics
Tumor-inducing genetic element
- tumor suppressorGene preventing uncontrolled growth
- locusParticular position or place
- alleleGene variant at one locus
- haploinsufficiencyLone working allele inadequate
Self-replicating DNA circle
- vectorQuantity with direction
- transgeneTransferred genetic sequence
- cloningMaking identical copies
- transformationThorough change in form
amplification
Increase in intensity
- deletionRemoval of content
- duplicationMaking an identical copy
- gainPositive return received
loss · segmental · polymorphism · submicroscopic · insertion · rearrangement · breakpoint · mosaic
trisomy
Three chromosomes, not two
- karyotypeOrganized chromosome display
- chromosomal disorderIllness from atypical cellular genetics
- Down syndromeThird chromosome 21 present
FISH
Chromosome sequence visualization method
- microarrayGene expression detection tool
- Southern blotDNA transfer and detection method
- sequencingDetermining element order
coverage · quantification · fluorescence · probe · hybridization · bioinformatics
oncogene
Tumor-inducing genetic element
- tumor suppressorGene preventing uncontrolled growth
- locusParticular position or place
- alleleGene variant at one locus
plasmid
Self-replicating DNA circle
- geneticsDNA, allele, genotype, genes, gene
- DNA AnalysisDNA, DNA profiling, DNA testing, DNA sequencing, DNA fingerprinting
- identifiersidentifier, title, rank, license, permit
- Organelle Geneticsmitochondrial DNA, maternal inheritance, haplogroup, haplogroups, haplotype
- Bioinformaticssequence alignment, DNA sequencing, homology, gene expression, gap
- Evolutionary Genomicshomology, divergence, convergent evolution, natural selection, genetic drift