colocalization
Molecules sharing location
Colocalization is the presence of two or more substances in the same location, used primarily in biology and microscopy.
When fluorescent markers for different proteins overlap in cell imaging, they show colocalization—evidence the proteins occupy the same cellular region and may interact: The study demonstrated colocalization of the receptor and its ligand.
Partial coincidence of coverage
- coincidenceUnplanned matching of events
- juxtapositionAdjacent contrasting placement
- proximityNearness in space
- alignmentCorrect relative positioning
superimposition · co-occurrence · adjacency · apposition · convergence · intersection · correlation · coexistence
Folded amino chain
- geneHereditary information unit
- compartmentalizationDivision into distinct sections
- organelleSubcellular functional unit
- cytoplasmGel surrounding the nucleus
nucleus · membrane · mitochondria · endoplasmic reticulum · Golgi · vesicle · translocation · subcellular
Light emitted after absorption
- confocalSharing a common focus
- microscopyTechnique using powerful lenses
- resolutionFormal decision or determination
- pixelSmallest display unit
overlay · channel · merge · signal-to-noise · laser · detector · Pearson · threshold
overlap
Partial coincidence of coverage
- coincidenceUnplanned matching of events
- juxtapositionAdjacent contrasting placement
- proximityNearness in space
alignment · superimposition · co-occurrence · adjacency · apposition · convergence · intersection · correlation · coexistence
protein
Folded amino chain
- geneHereditary information unit
- compartmentalizationDivision into distinct sections
- organelleSubcellular functional unit
cytoplasm · nucleus · membrane · mitochondria · endoplasmic reticulum · Golgi · vesicle · translocation · subcellular · trafficking
fluorescence
Light emitted after absorption
- confocalSharing a common focus
- microscopyTechnique using powerful lenses
- resolutionFormal decision or determination
pixel · overlay · channel · merge · signal-to-noise · laser · detector · Pearson · threshold · ROI
- Immunostainingprimary antibody, secondary antibody, antibody, antigen, DAB
- microscopymicroscope, objective lens, compound microscope, eyepiece, compound microscopes
- fluorescence microscopyfluorescent dye, fluorescein, CFP, confocal, spinning disk
colocalizationseparation
State of being apart
segregation · compartmentalization · exclusion · mutual exclusion · displacement
colocalizationindependence
Freedom from external control
disassociation · dissociation · negative correlation · mutual exclusivity · decoupling
local, location, locate, relocate, localized, localize, dislocate, localization, localizing