lab mice
Experimental animal subjects
Lab mice are mice bred and kept for scientific research, typically the house mouse species standardized for genetic uniformity.
They serve as model organisms in medical, pharmaceutical, and behavioral studies: The drug showed promise in lab mice but failed human trials.
The term often appears in discussions about whether research findings will translate to humans.
Barred enclosures for confinement
- beddingMaterials covering a mattress
- ventilationCirculation of fresh air
- enrichmentImprovement through addition
- nesting materialStuff birds build with
water bottles · feeders · racks · vivarium · SPF · temperature control · humidity · corn cob
Having inserted foreign genes
- knockoutIncapacitating final blow
- gene editingTargeted DNA alteration
- CRISPRGene-editing molecular machinery
- chromosomesGene-bearing nuclear structures
alleles · mutation · phenotype · genotype · DNA · recombination · gene therapy · loci
Systematic testing of ideas
- control groupUntreated subjects for comparison
- variablesChangeable elements in equations
- hypothesisTestable proposed explanation
- dataFacts for analysis
study · findings · publication · peer review · methodology · analysis · statistics · results
Study of disease processes
- oncologyCancer medicine specialty
- neurodegenerationProgressive loss of neurons
- cardiovascularOf heart and blood vessels
- diabetesMetabolic disorder affecting glucose
inflammation · infection · autoimmunity · obesity · metabolic syndrome · fibrosis · atherosclerosis · immunodeficiency
Non-human health and treatment
- three RsTraditional elementary curriculum
- replacementWhat takes another's place
- reductionMaking something smaller
- refinementElegance of manner
euthanasia · anesthesia · analgesia · suffering · sentience · animal rights · cruelty-free · alternatives
Puzzle of passages
- learningGaining knowledge gradually
- memoryMind's retention capacity
- cognitionMental knowledge acquisition
- conditioningLearned behavioral adaptation
reinforcement · habituation · open field · nest building · grooming · social interaction
cages
Barred enclosures for confinement
- beddingMaterials covering a mattress
- ventilationCirculation of fresh air
- enrichmentImprovement through addition
nesting material · water bottles · feeders · racks · vivarium · SPF · temperature control · humidity · corn cob · wood shavings
transgenic
Having inserted foreign genes
- knockoutIncapacitating final blow
- gene editingTargeted DNA alteration
- CRISPRGene-editing molecular machinery
chromosomes · alleles · mutation · phenotype · genotype · DNA · recombination · gene therapy · loci · traits
experimentation
Systematic testing of ideas
- control groupUntreated subjects for comparison
- variablesChangeable elements in equations
- hypothesisTestable proposed explanation
data · study · findings · publication · peer review · methodology · analysis · statistics · results · observation
pathology
Study of disease processes
- oncologyCancer medicine specialty
- neurodegenerationProgressive loss of neurons
- cardiovascularOf heart and blood vessels
diabetes · inflammation · infection · autoimmunity · obesity · metabolic syndrome · fibrosis · atherosclerosis · immunodeficiency
animal welfare
Non-human health and treatment
- three RsTraditional elementary curriculum
- replacementWhat takes another's place
- reductionMaking something smaller
refinement · euthanasia · anesthesia · analgesia · suffering · sentience · animal rights · cruelty-free · alternatives · in vitro
maze
Puzzle of passages
- learningGaining knowledge gradually
- memoryMind's retention capacity
- cognitionMental knowledge acquisition
conditioning · reinforcement · habituation · open field · nest building · grooming · social interaction
- animal testinganimal testing, vivisection, experimentation, medical experimentation, biomedical research
- lab sciencebiology, chemistry, physics, microbiology, biochemistry
- test subjectshuman subjects, guinea pigs, experimental group, control group, participants
- mouse geneticsembryonic stem cells, backcross, littermates, breeding colonies, agouti
- lab biologycell culture, petri dish, test tube, pipette, PCR
- Rodent ArtMickey Mouse, Ratatouille, Stuart Little
lab micepets
Domesticated companion animals
companion animals · therapy animals · hamsters · guinea pigs · service animals