hemophilia
Clotting factor deficiency
Hemophilia is a genetic disorder in which blood fails to clot normally, causing prolonged bleeding from even minor injuries.
The condition results from deficiency in clotting factors and occurs almost exclusively in males, though females can be carriers.
Hemophilia became widely known through its appearance in European royal families: Queen Victoria was a carrier of hemophilia.
Liquid solidifying into mass
- factor VIIICoagulation protein enabling clotting
- fibrinClot-forming protein
- thrombinSerine protease enabling coagulation
- prothrombinThrombin's inactive precursor
fibrinogen · hemostasis · clotting factor · clot formation · cofactor
Masked unless paired identically
- inheritanceProperty received from ancestors
- mutationPermanent DNA alteration
- carrierOne that transports
- chromosomeDNA strand carrying genes
hereditary · gene therapy · familial · pedigree · genetic counseling · genotype · phenotype · DNA
Profuse discharge of blood
- bruisingCausing tissue discoloration
- hematomaBlood collected outside vessels
- blood lossDepletion of vital fluid
- internal bleedingBlood pooling inside tissues
Supplying lacking substances medically
- prophylaxisPreventive medical treatment
- infusionSteeping to extract essence
- transfusionTransfer of blood intravenously
- hematologistPhysician specializing in blood
Disease affecting joints
- chronic painEnduring physical suffering
- mobility aidsEquipment supporting independent movement
- medical alertNotice of medical concern
- support groupsGatherings for shared struggles
coagulation
Liquid solidifying into mass
- factor VIIICoagulation protein enabling clotting
- fibrinClot-forming protein
- thrombinSerine protease enabling coagulation
prothrombin · fibrinogen · hemostasis · clotting factor · clot formation · cofactor
recessive
Masked unless paired identically
- inheritanceProperty received from ancestors
- mutationPermanent DNA alteration
- carrierOne that transports
chromosome · hereditary · gene therapy · familial · pedigree · genetic counseling · genotype · phenotype · DNA · allele
hemorrhage
Profuse discharge of blood
- bruisingCausing tissue discoloration
- hematomaBlood collected outside vessels
- blood lossDepletion of vital fluid
internal bleeding · petechiae · nosebleed · wound bleeding · purpura
replacement therapy
Supplying lacking substances medically
- prophylaxisPreventive medical treatment
- infusionSteeping to extract essence
- transfusionTransfer of blood intravenously
arthropathy
Disease affecting joints
- chronic painEnduring physical suffering
- mobility aidsEquipment supporting independent movement
- medical alertNotice of medical concern
support groups · quality of life · disability · patient advocacy
- Genetic Disorderscystic fibrosis, sickle cell disease, sickle cell anemia, sickle cell, Down syndrome
- Rare Diseasesprogeria, Tay-Sachs, Krabbe disease, PKU, tuberous sclerosis
- Genetic SyndromesDown syndrome, fragile X syndrome, DiGeorge syndrome, BRCA1, neurofibromatosis
- diseasescancer, diabetes, tuberculosis, influenza, measles
- chronic conditionsdiabetes, heart disease, asthma, arthritis, hypertension
- Blood Systemblood, blood cells, red blood cells, white blood cells, platelets
hemophiliathrombosis
Clot forming in vessel
deep vein thrombosis · pulmonary embolism · blood clot · embolism · clot formation