thrombin
Blood-clotting protein catalyst
Thrombin is an enzyme in blood that converts fibrinogen into fibrin, enabling clots to form.
It's central to the coagulation cascade—the chain reaction that stops bleeding when tissue is damaged.
Medical contexts use thrombin topically to control surgical bleeding: The surgeon applied thrombin to the wound site.
Blood solidifying process
- coagulationLiquid solidifying into mass
- plateletsCell fragments enabling coagulation
- fibrinClot-forming protein
- bloodBody's oxygen carrier
wound · plasma · clot · bleeding · hemorrhage · vascular · hemophilia · vessel
Liquid solidifying into mass
- fibrinogenPlasma protein for coagulation
- serineProtein-forming amino acid
- zymogenInactive enzyme precursor
- catalysisAccelerating reactions without consumption
cascade · substrate · fibrin · cleavage · proteolysis · activation · active site · factor Xa
Obstruction in blood vessel
- strokeSudden brain blood blockage
- pulmonary embolismClot blocking lung artery
- infarctionTissue necrosis from ischemia
- ischemiaInsufficient tissue blood supply
clotting
Blood solidifying process
- coagulationLiquid solidifying into mass
- plateletsCell fragments enabling coagulation
- fibrinClot-forming protein
blood · wound · plasma · clot · bleeding · hemorrhage · vascular · hemophilia · vessel · injury
coagulation
Liquid solidifying into mass
- fibrinogenPlasma protein for coagulation
- serineProtein-forming amino acid
- zymogenInactive enzyme precursor
catalysis · cascade · substrate · fibrin · cleavage · proteolysis · activation · active site · factor Xa · calcium
embolism
Obstruction in blood vessel
- strokeSudden brain blood blockage
- pulmonary embolismClot blocking lung artery
- infarctionTissue necrosis from ischemia
anticoagulant
Substance preventing blood clots
- heparinSubstance preventing coagulation
- warfarinClot-preventing medication
- embolismObstruction in blood vessel
vitamin K · coumarin · dosing · monitoring · reversal
- Blood Componentsred blood cells, white blood cells, plasma, platelets, erythrocytes
- blood clottingfibrin, fibrinogen, platelet, clot formation, clotting factors
- Blood Productswhole blood, plasma, platelets, red blood cells, red cells
- blood proteinsalbumin, globulin, globulins, fibrinogen, immunoglobulin
- coagulantsfibrinogen, fibrin, platelets, clotting factors, vitamin K
- enzymeslipase, amylase, protease, kinase, enzyme
- deep-vein thrombosisClot in lower limb vessel
- coronary thrombosisClot in cardiac artery
- deep vein thrombosisClot in leg vessel