5-fluorouracil
Antimetabolite cancer treatment
5-fluorouracil is a chemotherapy drug used to treat various cancers, particularly of the colon, breast, and skin.
Often abbreviated 5-FU, it works by interfering with DNA synthesis in rapidly dividing cells.
Applied topically, it treats precancerous skin lesions and superficial skin cancers: The dermatologist prescribed 5-fluorouracil cream for the actinic keratoses.
Anti-cancer drug treatment
- cancerUncontrolled cell proliferation disease
- tumorAbnormal tissue mass
- carcinomaEpithelial malignant tumor
- adenocarcinomaGlandular tissue malignancy
colorectal · breast cancer · gastric cancer · pancreatic cancer · metastasis · malignancy · neoplasm · adjuvant
Heterocyclic aromatic nitrogen compound
- DNA synthesisConstructing genetic material
- uracilRNA pyrimidine nucleobase
- nucleotideGenetic code subunit
- cell cycleReplication process of cells
replication · thymine · catabolism · anabolism · phosphorylation · metabolite
Steeping to extract essence
- intravenousInto the vein
- bolusChewed food mass
- topicalCurrently relevant or newsworthy
- creamRich milk fat
dosing · regimen · pump · port · central line · cycle · protocol · bioavailability
Low white cell count
- neutropeniaInsufficient neutrophils in blood
- anemiaRed cell deficiency
- stomatitisMouth membrane inflammation
- diarrheaFrequent liquid bowel movements
nausea · vomiting · alopecia · neurotoxicity · bone marrow · immunosuppression · fatigue · photosensitivity
chemotherapy
Anti-cancer drug treatment
- cancerUncontrolled cell proliferation disease
- tumorAbnormal tissue mass
- carcinomaEpithelial malignant tumor
adenocarcinoma · colorectal · breast cancer · gastric cancer · pancreatic cancer · metastasis · malignancy · neoplasm · adjuvant · palliative
pyrimidine
Heterocyclic aromatic nitrogen compound
- DNA synthesisConstructing genetic material
- uracilRNA pyrimidine nucleobase
- nucleotideGenetic code subunit
cell cycle · replication · thymine · catabolism · anabolism · phosphorylation · metabolite
infusion
Steeping to extract essence
- intravenousInto the vein
- bolusChewed food mass
- topicalCurrently relevant or newsworthy
cream · dosing · regimen · pump · port · central line · cycle · protocol · bioavailability · half-life
leukopenia
Low white cell count
- neutropeniaInsufficient neutrophils in blood
- anemiaRed cell deficiency
- stomatitisMouth membrane inflammation
diarrhea · nausea · vomiting · alopecia · neurotoxicity · bone marrow · immunosuppression · fatigue · photosensitivity · dermatitis
- Cytotoxinsmethotrexate, taxol, nitrogen mustard, antimetabolites, ricin
- nucleoside analogsacyclovir, AZT, valacyclovir, remdesivir
- apoptosis agents
- cytotoxicitycytotoxicity, cytotoxins, cell death, apoptosis, necrosis
- radiosensitizersoxygen, hyperthermia