cytotoxicity
Lethal to cells
Cytotoxicity is the quality of being toxic to cells—the capacity to damage or kill them.
The term appears most often in medical and pharmaceutical contexts: chemotherapy drugs are valued for their cytotoxicity against cancer cells, while researchers test new compounds for unwanted cytotoxicity to healthy tissue.
The study measured cytotoxicity at various concentrations.
Programmed cell death
- necrosisLocalized cell death
- cell deathCessation of cellular life
- cytolysisCell destruction by rupture
- autophagyCellular self-degradation process
Compositional evaluation procedure
- viabilityCapacity to succeed
- screeningEvaluative selection process
- in vitroIn an artificial environment
- cell cultureLaboratory technique for growing tissue
dose-response · biocompatibility · preclinical · validation · high-throughput · positive control · endpoint
Harmful effects on nerves
- LD50Half-fatal dose measurement
- dose-responseRelationship between amount and effect
- organ damageHarm to internal body parts
- biomarkersMeasurable disease indicators
Harmful biological substances
- poisonsHarmful ingested substances
- venomsPoisonous animal secretions
- ricinToxic castor compound
- arsenicToxic metalloid element
cyanide · mercury · lead · botulinum · strychnine · mycotoxins · hemlock · dioxin
Thymus-matured immune lymphocytes
- lymphocytesAdaptive immunity cells
- immunotherapyDisease treatment via body's defenses
- killer cellsImmune cells destroying pathogens
Epithelial malignant tumor
- leukemiaMalignancy of blood-forming tissues
- lymphomaCancer from immune cells
- metastasisCancer spreading beyond origin
- platinum-basedIncorporating element 78
antimetabolites · 5-fluorouracil · targeted therapy · drug resistance · combination therapy
apoptosis
Programmed cell death
- necrosisLocalized cell death
- cell deathCessation of cellular life
- cytolysisCell destruction by rupture
assay
Compositional evaluation procedure
- viabilityCapacity to succeed
- screeningEvaluative selection process
- in vitroIn an artificial environment
cell culture · dose-response · biocompatibility · preclinical · validation · high-throughput · positive control · endpoint
neurotoxicity
Harmful effects on nerves
- LD50Half-fatal dose measurement
- dose-responseRelationship between amount and effect
- organ damageHarm to internal body parts
toxins
Harmful biological substances
arsenic · cyanide · mercury · lead · botulinum · strychnine · mycotoxins · hemlock · dioxin · formaldehyde
T-cells
Thymus-matured immune lymphocytes
- lymphocytesAdaptive immunity cells
- immunotherapyDisease treatment via body's defenses
- killer cellsImmune cells destroying pathogens
carcinoma
Epithelial malignant tumor
- leukemiaMalignancy of blood-forming tissues
- lymphomaCancer from immune cells
- metastasisCancer spreading beyond origin
platinum-based · antimetabolites · 5-fluorouracil · targeted therapy · drug resistance · combination therapy
cytotoxicitybiocompatibility
Harmlessness to living systems
non-toxic · safety · tolerability · harmlessness · biosafety
toxin, toxicity, cytoplasm, cytology, toxicology, cytotoxic, cytotoxin, cytotoxins, cytogenesis