neurotoxicity
Nervous system damage
Neurotoxicity is the capacity of a substance to damage or destroy nerve tissue.
The term describes both the property itself and its effects: a chemical's neurotoxicity, or the neurotoxicity resulting from exposure.
Heavy metals, certain pesticides, and some medications can cause neurotoxicity, leading to symptoms ranging from numbness to cognitive impairment.
The drug was withdrawn due to neurotoxicity observed in clinical trials.
Dense metal, symbol Pb
- mercuryLiquid metallic element
- methylmercuryNeurotoxic organometallic compound
- arsenicToxic metalloid element
- cadmiumElement forty-eight
aluminum · organophosphates · pesticides · solvents · hexane · toluene · methanol · acrylamide
Abnormal skin sensation
- tremorsSlight shaking movements
- seizuresInvoluntary convulsions or takings
- ataxiaImpaired voluntary movement control
- memory lossFailure to recall
confusion · cognitive decline · weakness · headache · dizziness · vertigo · slurred speech · dysarthria
Progressive loss of neurons
- dementiaChronic cognitive impairment
- parkinsonismMotor syndrome with tremor, rigidity
- encephalopathyDisease impairing brain function
- neuritisInflamed neural tissue disorder
Neuron's signal-sending projection
- dendriteNeuron's input branch
- synapseNerve signal crossing point
- myelinNerve fiber insulation
- astrocyteStar-shaped neural support cell
microglia · ganglion · hippocampus · cerebellum · brainstem · basal ganglia · neocortex · peripheral nerve
Programmed cell death
- demyelinationNerve sheath degradation
- DNA damageInjury to genetic material
Study of nerve poisons
- electrophysiologyBiology's electrical activity science
- histopathologyDisease study through tissue
- biomarkersMeasurable disease indicators
- exposure assessmentEvaluating contamination intake levels
dose-response · animal models · neuroimaging · cell culture · risk assessment · screening
lead
Dense metal, symbol Pb
- mercuryLiquid metallic element
- methylmercuryNeurotoxic organometallic compound
- arsenicToxic metalloid element
cadmium · aluminum · organophosphates · pesticides · solvents · hexane · toluene · methanol · acrylamide · dioxins
paresthesia
Abnormal skin sensation
- tremorsSlight shaking movements
- seizuresInvoluntary convulsions or takings
- ataxiaImpaired voluntary movement control
memory loss · confusion · cognitive decline · weakness · headache · dizziness · vertigo · slurred speech · dysarthria · hallucinations
neurodegeneration
Progressive loss of neurons
- dementiaChronic cognitive impairment
- parkinsonismMotor syndrome with tremor, rigidity
- encephalopathyDisease impairing brain function
neuritis · cognitive impairment · bioaccumulation · dose-response
axon
Neuron's signal-sending projection
astrocyte · microglia · ganglion · hippocampus · cerebellum · brainstem · basal ganglia · neocortex · peripheral nerve
apoptosis
Programmed cell death
- demyelinationNerve sheath degradation
- DNA damageInjury to genetic material
neurotoxicology
Study of nerve poisons
- electrophysiologyBiology's electrical activity science
- histopathologyDisease study through tissue
- biomarkersMeasurable disease indicators
exposure assessment · dose-response · animal models · neuroimaging · cell culture · risk assessment · screening
- chemical hazardspoisoning, carcinogenicity, fumes, vapors, chemical burns
- drug effectsanalgesia, allergic reaction, stimulation, vasodilation, vasoconstriction
- drug reactionsadverse reaction, adverse reactions, side effects, drug allergy, allergic reaction
- poisoningarsenic poisoning, cyanide poisoning, food poisoning, carbon monoxide poisoning, lead poisoning
- toxic metalsarsenic, cadmium, chromium, nickel, lead poisoning
- toxicologytoxicology, poison, venom, poisons, dose-response
neurotoxicitycognitive enhancement
Improving mental function artificially
toxic, toxin, intoxicate, neural, neuron, intoxication, toxicity, neurological, neuroscience