antimetabolites
Cellular process disruptors
Antimetabolites are drugs that interfere with cell metabolism by mimicking substances cells need to function and divide.
They work by substituting for natural molecules, disrupting DNA synthesis or other cellular processes.
Used primarily in cancer chemotherapy and treating autoimmune diseases: Methotrexate is one of the oldest and most widely used antimetabolites.
Two-fused-ring nitrogenous base
- pyrimidineHeterocyclic aromatic nitrogen compound
- nucleotideGenetic code subunit
- biosynthesisLiving production of molecules
- folic acidB-vitamin preventing birth defects
DNA synthesis · analogues · enzymatic · adenine · thymine · cytosine · guanine · uracil
Anti-cancer drug treatment
- tumorsAbnormal tissue masses
- neoplasmsAbnormal tissue masses
- leukemiaMalignancy of blood-forming tissues
- lymphomaCancer from immune cells
carcinoma · proliferation · metastasis · DNA replication · apoptosis · bone marrow · remission · combination therapy
Mental check on behavior
- blockadeSealing off a place
- suppressionForcible prevention or concealment
- interferenceUnwelcome involvement in affairs
- cytotoxicityHarmfulness to living cells
purine
Two-fused-ring nitrogenous base
- pyrimidineHeterocyclic aromatic nitrogen compound
- nucleotideGenetic code subunit
- biosynthesisLiving production of molecules
folic acid · DNA synthesis · analogues · enzymatic · adenine · thymine · cytosine · guanine · uracil · coenzyme
chemotherapy
Anti-cancer drug treatment
- tumorsAbnormal tissue masses
- neoplasmsAbnormal tissue masses
- leukemiaMalignancy of blood-forming tissues
lymphoma · carcinoma · proliferation · metastasis · DNA replication · apoptosis · bone marrow · remission · combination therapy · adjuvant
methotrexate
Antifolate chemotherapy agent
- 5-fluorouracilAntineoplastic pyrimidine antagonist
inhibition
Mental check on behavior
- blockadeSealing off a place
- suppressionForcible prevention or concealment
- interferenceUnwelcome involvement in affairs
antimetabolitesmetabolites
Chemicals from bodily processes
cofactors · coenzymes · vitamins · essential nutrients · amino acids
metabolism, metabolic, metabolize, metabolite, metabolites, metabolically