monoclonal antibodies
Identical immune proteins
Monoclonal antibodies are laboratory-made proteins designed to target specific cells or substances in the body.
Unlike natural antibodies produced by many different immune cells, monoclonal antibodies are clones from a single cell line, making them uniform and precise.
They're used to treat cancers, autoimmune diseases, and infections: The patient received monoclonal antibodies for her rheumatoid arthritis.
Drug names often end in -mab.
Fused immortal antibody-producer
- cell cultureLaboratory technique for growing tissue
- bioreactorVessel for growing organisms
- recombinantGenetically engineered combination
- purificationRemoval of contaminants
bioprocessing · humanized · chimeric · scale-up · perfusion · quality control · titer · harvest
Medical intervention for malignancy
- cytotoxicityHarmfulness to living cells
- lymphomaCancer from immune cells
- leukemiaMalignancy of blood-forming tissues
- melanomaAggressive pigment-cell cancer
HER2 · infusion · oncology · combination therapy · clinical trials · remission
Antibody binding region
- affinityNatural liking or attraction
- selectivityTendency to choose carefully
- binding siteMolecular attachment region
- complementarityMutual enhancement through difference
Misdirected immunity causing illness
- rheumatoid arthritisAutoimmune joint disease
- Crohn's diseaseChronic intestinal inflammation disorder
- psoriasisImmune system attacks skin cells
- macular degenerationRetinal disease causing central blindness
transplant rejection · biosimilars · FDA approval · blockbuster drug · subcutaneous · intravenous · dosing · half-life
hybridoma
Fused immortal antibody-producer
- cell cultureLaboratory technique for growing tissue
- bioreactorVessel for growing organisms
- recombinantGenetically engineered combination
purification · bioprocessing · humanized · chimeric · scale-up · perfusion · quality control · titer · harvest
cancer treatment
Medical intervention for malignancy
- cytotoxicityHarmfulness to living cells
- lymphomaCancer from immune cells
- leukemiaMalignancy of blood-forming tissues
melanoma · HER2 · infusion · oncology · combination therapy · clinical trials · remission
epitope
Antibody binding region
- affinityNatural liking or attraction
- selectivityTendency to choose carefully
- binding siteMolecular attachment region
complementarity · cross-reactivity · off-target · precision · avidity
autoimmune disease
Misdirected immunity causing illness
- rheumatoid arthritisAutoimmune joint disease
- Crohn's diseaseChronic intestinal inflammation disorder
- psoriasisImmune system attacks skin cells
macular degeneration · transplant rejection · biosimilars · FDA approval · blockbuster drug · subcutaneous · intravenous · dosing · half-life · drug development
- Medical Advancespenicillin, vaccine, X-ray, insulin pump, pacemaker
- Medical Sciencegenetics, immunology, antibiotics, penicillin, DNA
- Medicinespill, tablet, aspirin, tablets, penicillin
- pandemiclockdowns, COVID-19, outbreak, epidemic, COVID
- BiotechDNA, bioengineering, genetic testing, gene, DNA sequencing
- COVID-19COVID-19, spike protein, mRNA vaccines, omicron, variants
clone, clones, antibody, cloning, cloned, antibodies, clonal, monoclonal