globin
Hemoglobin's protein half
Globin is a type of protein that combines with other molecules to form compounds essential for transporting oxygen in the body.
Hemoglobin, the oxygen-carrying molecule in red blood cells, consists of globin proteins bound to heme groups.
Sickle cell disease results from a mutation in the globin gene.
Iron-porphyrin complex in blood
- ironElement twenty-six
- polypeptideAmino acid polymer
- conformationStructural form or arrangement
- foldingBending something over itself
subunit · chain · binding site · ligand · affinity · denaturation
Inherited blood cell malformation
- thalassemiaHereditary hemoglobin production defect
- anemiaRed cell deficiency
- polycythemiaElevated red cell count
- hemolysisRed blood cell destruction
pernicious anemia · hemochromatosis · bilirubin · jaundice · genetic mutation · carrier · blood transfusion · hydrops fetalis
Oxygen-transporting components of circulation
- erythrocytesOxygen-carrying blood cells
- hematocritRed cell volume fraction
- oxygen saturationBlood's carried gas level
- carbon dioxideRespiration byproduct, photosynthesis fuel
deoxyhemoglobin · hypoxia · cyanosis · arterial blood · venous blood · hematopoiesis
DNA to functional product
- mutationPermanent DNA alteration
- polymorphismMany forms, one interface
- hereditaryPassed through generations
- alleleGene variant at one locus
genotype · phenotype · transcription · splicing · promoter · enhancer
heme
Iron-porphyrin complex in blood
- ironElement twenty-six
- polypeptideAmino acid polymer
- conformationStructural form or arrangement
folding · subunit · chain · binding site · ligand · affinity · denaturation
sickle cell
Inherited blood cell malformation
- thalassemiaHereditary hemoglobin production defect
- anemiaRed cell deficiency
- polycythemiaElevated red cell count
hemolysis · pernicious anemia · hemochromatosis · bilirubin · jaundice · genetic mutation · carrier · blood transfusion · hydrops fetalis
red blood cells
Oxygen-transporting components of circulation
- erythrocytesOxygen-carrying blood cells
- hematocritRed cell volume fraction
- oxygen saturationBlood's carried gas level
carbon dioxide · deoxyhemoglobin · hypoxia · cyanosis · arterial blood · venous blood · hematopoiesis
gene expression
DNA to functional product
- mutationPermanent DNA alteration
- polymorphismMany forms, one interface
- hereditaryPassed through generations
allele · genotype · phenotype · transcription · splicing · promoter · enhancer
leghemoglobin
Legume nodule oxygen-binding protein
- snow globeSealed sphere with drifting flakes
- Golden GlobeFilm and television prize
- globe trotterHabitual worldwide traveler
- spinning globeRotating model of Earth
- plasma globeGlass ball with electrical filaments
- desk globeMounted spherical world map
globe, globular, globule, hemoglobin, myoglobin, globules, globins, hemoglobins, oxyhemoglobin