clotting factors
Blood-thickening enzymes
Clotting factors are proteins in blood that work together to form clots and stop bleeding.
When tissue is damaged, these factors activate in a cascade—each triggering the next—until a stable clot forms.
Hemophilia results from deficiency in specific clotting factors.
Medical contexts number them with Roman numerals: Factor VIII deficiency causes hemophilia A.
Plasma protein for coagulation
- prothrombinThrombin's inactive precursor
- thrombinSerine protease enabling coagulation
- fibrinClot-forming protein
- vitamin KFat-soluble clotting agent
phospholipids · zymogen · cofactor · activation · extrinsic pathway
Cell fragments enabling coagulation
- hemorrhageProfuse discharge of blood
- bleedingBlood loss from injury
- thrombosisClot forming in vessel
- wound healingRestoration after injury
vasoconstriction · blood loss · bleeding disorders · petechiae · hematoma
Property received from ancestors
- mutationsAlterations in genetic sequence
- carrierOne that transports
- genetic testingAnalysis for inherited disorders
- gene therapyMedical DNA modification treatment
deficiency · polymorphisms · hereditary · congenital · acquired
Clot-preventing medications
fibrinogen
Plasma protein for coagulation
- prothrombinThrombin's inactive precursor
- thrombinSerine protease enabling coagulation
- fibrinClot-forming protein
vitamin K · phospholipids · zymogen · cofactor · activation · extrinsic pathway
platelets
Cell fragments enabling coagulation
- hemorrhageProfuse discharge of blood
- bleedingBlood loss from injury
- thrombosisClot forming in vessel
wound healing · vasoconstriction · blood loss · bleeding disorders · petechiae · hematoma
inheritance
Property received from ancestors
- mutationsAlterations in genetic sequence
- carrierOne that transports
- genetic testingAnalysis for inherited disorders
gene therapy · deficiency · polymorphisms · hereditary · congenital · acquired
anticoagulants
Clot-preventing medications
- bloodblood, plasma, platelet, platelets, red blood cell
- Blood Systemblood, blood cells, red blood cells, white blood cells, platelets
- pharmaceuticalsanalgesics, medicines, anesthetics, pills, acetaminophen
- Blood Componentsred blood cells, white blood cells, plasma, platelets, erythrocytes
- blood traitsblood type, blood pressure, blood volume, blood sugar, hemoglobin
- lab testsblood test, blood tests, CBC, urinalysis, complete blood count
clotting factorsanticoagulants
Clot-preventing medications
thrombolytics · blood thinners · plasmin · heparin · warfarin