mutagenesis
Creating genetic alterations
Mutagenesis is the process by which genetic material undergoes mutation—a change in its DNA sequence.
It can occur naturally through errors in cell replication or be induced deliberately by radiation, chemicals, or laboratory techniques.
Scientists use mutagenesis to study gene function or develop new traits in organisms: site-directed mutagenesis allows researchers to alter specific DNA sequences.
Cancer-promoting agent
- radiationEnergy propagation through space
- ultravioletWavelengths shorter than violet
- X-raysShort-wavelength penetrating light
- nitrosaminesCarcinogenic nitrogen-oxygen compounds
formaldehyde · asbestos · EMS
Gene variant at one locus
- genotypeOrganism's complete allele set
- phenotypeObservable characteristics of organism
- wild-typeOriginal genetic baseline
- locusParticular position or place
gene · chromosome · genome · heritability · recombination · polymorphism · variant · heterozygous
Occurring without pattern
- CRISPRGene-editing molecular machinery
- plasmidSelf-replicating DNA circle
- vectorQuantity with direction
- transformationThorough change in form
screening · selection · sequencing · cloning
Placing something within
- deletionRemoval of content
- frameshiftAltered reading of codons
- substitutionExchange of one for another
- transitionChange from one state
alkylation · deamination · intercalation · duplication · inversion · translocation · lesion
Change from a norm
- fitnessGood physical shape
- adaptationFitting to new conditions
- speciationFormation of distinct species
Tumor-inducing genetic element
- cancerUncontrolled cell proliferation disease
- predispositionInnate tendency toward something
- biomarkerMeasurable biological health signal
- toxicologyScience of poisons
carcinogen
Cancer-promoting agent
- radiationEnergy propagation through space
- ultravioletWavelengths shorter than violet
- X-raysShort-wavelength penetrating light
nitrosamines · formaldehyde · asbestos · EMS
allele
Gene variant at one locus
- genotypeOrganism's complete allele set
- phenotypeObservable characteristics of organism
- wild-typeOriginal genetic baseline
locus · gene · chromosome · genome · heritability · recombination · polymorphism · variant · heterozygous · homozygous
random
Occurring without pattern
- CRISPRGene-editing molecular machinery
- plasmidSelf-replicating DNA circle
- vectorQuantity with direction
transformation · screening · selection · sequencing · cloning
insertion
Placing something within
- deletionRemoval of content
- frameshiftAltered reading of codons
- substitutionExchange of one for another
transition · alkylation · deamination · intercalation · duplication · inversion · translocation · lesion
variation
Change from a norm
- fitnessGood physical shape
- adaptationFitting to new conditions
- speciationFormation of distinct species
oncogene
Tumor-inducing genetic element
- cancerUncontrolled cell proliferation disease
- predispositionInnate tendency toward something
- biomarkerMeasurable biological health signal
generation, generate, mutation, genetic, genesis, mutant, transmutation, mutants, mutability