pKa

Proton donation strength

pKa is a measure of acid strength in chemistry—specifically, the negative logarithm of an acid's dissociation constant.

Lower pKa values indicate stronger acids that more readily donate protons.

The scale helps predict how substances behave in solution: Acetic acid has a pKa of about 4.76, making it a weak acid.

Chemists use pKa to understand drug absorption, buffer systems, and reaction mechanisms.

acidity

proton

Positive nuclear particle

buffer · ionization · phenol · logarithm · basic · neutral · hydroxyl

pharmacology

bioavailability

Fraction reaching active circulation

aspirin · ibuprofen · morphine · barbiturate · solubility · formulation · excretion

measurement

indicator

Sign revealing status

calibration · aqueous solution · activity coefficient · thermodynamic · tautomer

biochemistry

histidine

Amino acid, essential early

lysine · protein folding · catalysis · side chain · nucleophile · electrophile · peptide · hemoglobin · metabolite · cofactor

Categories
Opposites
acid-base measurement direction

pKaKb

1,024 bytes of data

basicity

Family

acid, acids, acidic, acidity, acidify, acidification

Familiarity
Top 2,000,000
Profile
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