Barbara McClintock

Barbara McClintock (1902–1992) was an American geneticist who discovered genetic transposition—the ability of genes to move within chromosomes.

Her work on maize chromosomes in the 1940s and 1950s was largely ignored for decades, considered too radical by the scientific establishment.

She was vindicated when molecular biology caught up, receiving the Nobel Prize in Physiology or Medicine in 1983.

McClintock became a symbol of scientific persistence and the eventual recognition of paradigm-shifting work.

cytogenetics

chromosomes

Gene-bearing nuclear structures

  • karyotypeOrganized chromosome display
  • mitosisNuclear division producing identical cells
  • meiosisGamete-producing cell division

nucleus · translocation · inversion · duplication · deletion · breakage · fusion · crossing over · linkage · genetic markers

maize

corn

Cereal grown on cobs

ear · husk · stalk · tassel · pericarp · endosperm · germplasm · cultivar · pollination · pigmentation

transposons

activator

Agent that initiates

gene regulation · mutation · genome · heredity · epigenetics · gene expression

pioneer

trailblazer

First to forge ahead

nonconformist · pathfinder · forerunner · revolutionary · vindication · persistence · overlooked · underappreciated · rediscovery · intuition

Nobel

laureate

Celebrated achievement recipient

ceremony · 1983 · Physiology · recognition · achievement · unshared · academy · banquet · diploma · gold

Categories
Opposites
recognition and establishment acceptance

Barbara McClintockFrancis Crick

Jonas Salk

scientific fraudulence

Barbara McClintockpseudoscientists

False claimants to rigor

Family

barbaric, barbarian, Barbie, Barbera, Barbara

Familiarity
Top 1,000,000
Profile
Mostly American · Timeless · Concrete · Rated G