sickle cell anaemia
Inherited blood disease
Sickle cell anaemia is a hereditary blood disorder in which red blood cells become rigid and crescent-shaped, obstructing blood flow and causing pain, organ damage, and shortened lifespan.
The condition predominantly affects people of African, Mediterranean, and South Asian descent.
Carriers of a single gene copy have some resistance to malaria, explaining the trait's persistence in populations from malaria-endemic regions.
Erythrocyte's oxygen-binding protein
- erythrocytesOxygen-carrying blood cells
- red blood cellsOxygen-transporting components of circulation
- hemolysisRed blood cell destruction
- hematocritRed cell volume fraction
bilirubin · jaundice · hypoxia · ischemia · bone marrow · transfusion · blood count
Property received from ancestors
- recessiveMasked unless paired identically
- carrierOne that transports
- alleleGene variant at one locus
- genotypeOrganism's complete allele set
phenotype · mutation · point mutation · nucleotide · substitution · codon · chromosome · DNA
Infusing donated cells intravenously
- bone marrow transplantInfusing healthy hematopoietic cells
- stem cell transplantInfusion of blood-forming precursors
- folic acidB-vitamin preventing birth defects
- pain managementReducing patient suffering medically
Sudden brain blood blockage
- priapismSustained pathological erection
- leg ulcersOpen wounds on lower limbs
- gallstonesHardened bile deposits
- retinopathyDisease of eye's photosensitive layer
kidney damage · osteomyelitis · infection · sepsis · organ damage · pneumonia
Lasting entire existence
- incurableCannot be healed
- fatigueWeariness from prolonged exertion
- managementOrganizing and directing resources
- monitoringOngoing observation of something
hospitalization · outpatient · healthcare · quality of life · caregiver · support · adaptation · resilience
Decisive dangerous moment
- throbbingRhythmic painful pulsing
- achingExperiencing dull pain
- excruciatingCausing extreme suffering
- bone painDiscomfort in skeletal tissue
joint pain · abdominal pain · chest pain · opioids · analgesics · acute · chronic pain · inflammation
hemoglobin
Erythrocyte's oxygen-binding protein
- erythrocytesOxygen-carrying blood cells
- red blood cellsOxygen-transporting components of circulation
- hemolysisRed blood cell destruction
hematocrit · bilirubin · jaundice · hypoxia · ischemia · bone marrow · transfusion · blood count
inheritance
Property received from ancestors
genotype · phenotype · mutation · point mutation · nucleotide · substitution · codon · chromosome · DNA · genetic counseling
blood transfusion
Infusing donated cells intravenously
- bone marrow transplantInfusing healthy hematopoietic cells
- stem cell transplantInfusion of blood-forming precursors
- folic acidB-vitamin preventing birth defects
pain management · gene therapy · immunization · hydration · oxygen therapy
stroke
Sudden brain blood blockage
- priapismSustained pathological erection
- leg ulcersOpen wounds on lower limbs
- gallstonesHardened bile deposits
retinopathy · kidney damage · osteomyelitis · infection · sepsis · organ damage · pneumonia
lifelong
Lasting entire existence
- incurableCannot be healed
- fatigueWeariness from prolonged exertion
- managementOrganizing and directing resources
monitoring · hospitalization · outpatient · healthcare · quality of life · caregiver · support · adaptation · resilience · disability
crisis
Decisive dangerous moment
- throbbingRhythmic painful pulsing
- achingExperiencing dull pain
- excruciatingCausing extreme suffering
bone pain · joint pain · abdominal pain · chest pain · opioids · analgesics · acute · chronic pain · inflammation · suffering
sickle cell anaemiainfectious disease
Pathogen-caused transmissible ailment
occupational disease · food poisoning · lifestyle disease · malaria · HIV/AIDS
sickle cell anaemiabacterial infection
Illness from harmful microorganisms
strep throat · acute illness · appendicitis · broken bone · pneumonia
sickle, anaemia, anemia, sickled, sickles, sickling, celled, cellular, cellar