receptor-mediated
Through molecular docking
Receptor-mediated describes biological processes that occur through specific receptor proteins on cell surfaces.
When a molecule binds to its matching receptor, it triggers a cellular response—like a key fitting a lock.
The term appears in biochemistry and pharmacology: receptor-mediated endocytosis, receptor-mediated drug delivery.
Many drugs work by exploiting receptor-mediated pathways.
Small fluid-filled sac
- internalizationAbsorbing ideas as one's own
- phagocytosisCellular ingestion of particles
- uptakeAbsorption or understanding
- endosomeMembrane sac for internalized cargo
cargo · lysosome · sorting · invagination · engulfment
Signal or energy transformation
- cascadeSuccessive downward flow
- phosphorylationPhosphate group attachment process
- kinasePhosphate-transferring enzyme
- activationSetting into operation
downstream · tyrosine · effector · amplification · pathway · intracellular · cross-talk · desensitization
Absorption or understanding
- poisoningHarmful substance exposure
- neurotoxinPoison attacking neural tissue
- diphtheriaBacterial throat membrane disease
- ricinToxic castor compound
anthrax · botulinum · intoxication · cytotoxicity · susceptibility · tropism · hijacking · exploitation
Tendency to choose carefully
- affinityNatural liking or attraction
- therapeuticPromoting healing or wellness
- blockerSomething that obstructs
- modulatorDevice that varies signals
inhibitor · dose-response · specificity · competitive · potency · bioavailability · antagonism · off-target
vesicle
Small fluid-filled sac
- internalizationAbsorbing ideas as one's own
- phagocytosisCellular ingestion of particles
- uptakeAbsorption or understanding
endosome · cargo · lysosome · sorting · invagination · engulfment
transduction
Signal or energy transformation
- cascadeSuccessive downward flow
- phosphorylationPhosphate group attachment process
- kinasePhosphate-transferring enzyme
activation · downstream · tyrosine · effector · amplification · pathway · intracellular · cross-talk · desensitization · agonist
uptake
Absorption or understanding
- poisoningHarmful substance exposure
- neurotoxinPoison attacking neural tissue
- diphtheriaBacterial throat membrane disease
ricin · anthrax · botulinum · intoxication · cytotoxicity · susceptibility · tropism · hijacking · exploitation · virulence
selectivity
Tendency to choose carefully
- affinityNatural liking or attraction
- therapeuticPromoting healing or wellness
- blockerSomething that obstructs
modulator · inhibitor · dose-response · specificity · competitive · potency · bioavailability · antagonism · off-target · clinical
- cell membranescell membrane, plasma membrane, nuclear membrane, bilayer, phospholipid
- Endocytosisendosome, internalization, phagocytosis, macropinocytosis, invagination
receptor-mediatedosmosis
Solvent crossing semipermeable barrier
receptor-mediatednon-specific
Not clearly defined
constitutive · spontaneous · unregulated · indiscriminate · basal
mediator, mediate, mediation, intermediate, receptive, intermediary, mediated, premeditation, receptor