porphobilinogen
Heme synthesis intermediate
Porphobilinogen is a chemical compound that serves as a building block in the body's production of heme—the iron-containing part of hemoglobin that carries oxygen in blood.
Elevated levels in urine indicate certain metabolic disorders, particularly acute intermittent porphyria: The lab tested for porphobilinogen to rule out porphyria.
Iron-porphyrin complex in blood
- precursorSomething that comes first
- pathwayDesignated route for travel
- intermediatesThings between endpoints
- synthaseBond-forming enzyme
uroporphyrinogen · substrate · mitochondria · cytosol · condensation · regulation · enzyme · catalysis
Renal excretion fluid
- diagnosisIdentification of illness
- screeningEvaluative selection process
- mutationPermanent DNA alteration
- attackAggressive act against another
abdominal pain · neuropsychiatric · photosensitivity · genetic testing · crisis · triggers · glucose · fasting
Erythrocyte's oxygen-binding protein
- myoglobinMuscle's oxygen-binding protein
- cytochromesElectron-transferring heme proteins
- chlorophyllLight-harvesting plant pigment
- catalasePeroxide-degrading enzyme
peroxidase · iron · magnesium · blood · erythrocytes · photosynthesis · pigments · bilirubin
heme
Iron-porphyrin complex in blood
- precursorSomething that comes first
- pathwayDesignated route for travel
- intermediatesThings between endpoints
uroporphyrinogen · synthase · substrate · mitochondria · cytosol · condensation · regulation · enzyme · catalysis · succinyl-CoA
urine
Renal excretion fluid
- diagnosisIdentification of illness
- screeningEvaluative selection process
- mutationPermanent DNA alteration
attack · abdominal pain · neuropsychiatric · photosensitivity · genetic testing · crisis · triggers · glucose · fasting · neurotoxicity
hemoglobin
Erythrocyte's oxygen-binding protein
- myoglobinMuscle's oxygen-binding protein
- cytochromesElectron-transferring heme proteins
- chlorophyllLight-harvesting plant pigment
catalase · peroxidase · iron · magnesium · blood · erythrocytes · photosynthesis · pigments · bilirubin · red blood cells
- heme biochemistryheme, hemoglobin, globin, myoglobin, oxyhemoglobin
- Heme Synthesisheme, uroporphyrinogen, succinyl-CoA, glycine
- biosynthesis intermediatesshikimic acid, phosphoenolpyruvate, acetyl-CoA
- Porphyrinsuroporphyrin, coproporphyrin, heme, uroporphyrinogen
- metabolitespyruvate, lactate, glucose, citrate, acetyl-CoA
- bilirubinbilirubin, conjugated bilirubin, jaundice, neonatal jaundice