monogenic
From one gene
Monogenic describes traits or disorders controlled by a single gene, as opposed to those involving multiple genes (polygenic).
In genetics, monogenic diseases like cystic fibrosis or sickle cell anemia follow predictable inheritance patterns: Monogenic conditions are easier to trace through family trees.
In geology, monogenic volcanoes form from a single eruption event.
Having superior influence
- recessiveMasked unless paired identically
- MendelianPertaining to inheritance laws
- alleleGene variant at one locus
- mutationPermanent DNA alteration
carrier · pedigree · Punnett square · penetrance · expressivity · heterozygous · homozygous · genotype
Genetic disorder thickening mucus
- sickle cell anemiaHereditary hemoglobin mutation disease
- Huntington's diseaseInherited fatal neurodegenerative condition
- hemophiliaGenetic clotting impairment
- Tay-Sachs diseaseHereditary enzyme deficiency disorder
muscular dystrophy · thalassemia · albinism · diagnostic testing · newborn screening · rare disease
Particular position or place
- allelicOf gene alternatives
- point mutationSingle nucleotide change in DNA
- nucleotideGenetic code subunit
- haploinsufficiencyLone working allele inadequate
gain-of-function · nonsense · frameshift · deletion · insertion · polymorphism · deleterious · pathogenic
Of single breed ancestry
- pedigreeRecord of descent
- bloodlineAncestry through generations
- lineageDescent from progenitors
- strainExcessive stretching force
stock · inbred · cultivar · selection · progeny · homozygosity · breed standard · heritage breed
dominant
Having superior influence
- recessiveMasked unless paired identically
- MendelianPertaining to inheritance laws
- alleleGene variant at one locus
mutation · carrier · pedigree · Punnett square · penetrance · expressivity · heterozygous · homozygous · genotype · phenotype
cystic fibrosis
Genetic disorder thickening mucus
- sickle cell anemiaHereditary hemoglobin mutation disease
- Huntington's diseaseInherited fatal neurodegenerative condition
- hemophiliaGenetic clotting impairment
Tay-Sachs disease · muscular dystrophy · thalassemia · albinism · diagnostic testing · newborn screening · rare disease
locus
Particular position or place
- allelicOf gene alternatives
- point mutationSingle nucleotide change in DNA
- nucleotideGenetic code subunit
haploinsufficiency · gain-of-function · nonsense · frameshift · deletion · insertion · polymorphism · deleterious · pathogenic · variant
purebred
Of single breed ancestry
strain · stock · inbred · cultivar · selection · progeny · homozygosity · breed standard · heritage breed
- geneticsDNA, allele, genotype, genes, gene
- Genetic Traitshair color, dark hair, skin color, dimples, blood type
monogenicnonheritable
Not genetically transmitted
nongenetic · acquired · environmental · noninherited · sporadic
genetic, genealogy, genetics, mono, homogenous, biogenesis, morphogenesis, polygenic, pathogenesis