monoclonal
From one cell
Monoclonal describes cells or antibodies derived from a single clone, making them genetically identical.
Monoclonal antibodies are produced in laboratories for medical use—targeting specific proteins in cancer treatment, autoimmune diseases, and diagnostic tests: The monoclonal antibody therapy helped shrink the tumor.
Contrast with polyclonal, derived from multiple cell lines.
Fused immortal antibody-producer
- immunoglobulinDefensive blood protein
- antigenImmune response inducer
- epitopeAntibody binding region
- specificityExactness of detail
binding · therapeutic · biosimilar · humanized · chimeric · murine · affinity · selectivity
Fused immortal antibody-producer
- bioreactorVessel for growing organisms
- purificationRemoval of contaminants
- fermentationMicrobial sugar conversion
- myelomaMalignant plasma cell neoplasm
fusion · immortalized · scale-up · bioprocessing · harvest · upstream · downstream · transfection
Exactly the same
- homogeneousAlike in composition throughout
- specificityExactness of detail
- consistencyReliable adherence to standards
- reproducibilityAbility to repeat findings
standardized · purity · characterized · defined · predictable
Cancer medicine specialty
- immunotherapyDisease treatment via body's defenses
- autoimmuneBody attacks itself
- psoriasisImmune system attacks skin cells
- infusionSteeping to extract essence
injection · remission · disease-modifying · targeted · antitumor · biopharmaceutical
Act of finding something
- biomarkerMeasurable biological health signal
- sensitivityResponsiveness to stimuli
- specificityExactness of detail
- fluorescentEmitting light when energized
hybridoma
Fused immortal antibody-producer
- immunoglobulinDefensive blood protein
- antigenImmune response inducer
- epitopeAntibody binding region
specificity · binding · therapeutic · biosimilar · humanized · chimeric · murine · affinity · selectivity · biologic
hybridoma
Fused immortal antibody-producer
- bioreactorVessel for growing organisms
- purificationRemoval of contaminants
- fermentationMicrobial sugar conversion
myeloma · fusion · immortalized · scale-up · bioprocessing · harvest · upstream · downstream · transfection · yield
identical
Exactly the same
- homogeneousAlike in composition throughout
- specificityExactness of detail
- consistencyReliable adherence to standards
reproducibility · standardized · purity · characterized · defined · predictable
oncology
Cancer medicine specialty
- immunotherapyDisease treatment via body's defenses
- autoimmuneBody attacks itself
- psoriasisImmune system attacks skin cells
infusion · injection · remission · disease-modifying · targeted · antitumor · biopharmaceutical
detection
Act of finding something
- biomarkerMeasurable biological health signal
- sensitivityResponsiveness to stimuli
- specificityExactness of detail
- pandemiclockdowns, COVID-19, outbreak, epidemic, COVID
- BiotechDNA, bioengineering, genetic testing, gene, DNA sequencing
- antibodiesantibody, antibodies, heavy chain, nanobodies, antibody response
- diagnosticsCT scan, rapid test, blood test, physical exam, antigen test
- serologyserum, antibody, antigen, titer, seropositive
- immunoassaysantigen test, lateral flow test, EIA, VDRL test, Wassermann test
- monoclonal antibodiesIdentical lab-cloned immune proteins
- monoclonal antibodyEngineered protein from cloned cells