organogenesis

Fetal architecture emerging

Organogenesis is the biological process by which organs form and develop, particularly during embryonic growth.

Cells differentiate and organize into distinct structures—heart, liver, brain—each with specialized functions.

The term appears in developmental biology and medicine: Organogenesis occurs primarily during the first trimester of pregnancy.

In tissue engineering, organogenesis describes growing organs artificially from stem cells.

embryonic

embryo

Organism before birth

mesoderm · endoderm · primordium · cell fate · patterning · blastocyst · embryogenesis · fetus · gestation · trimester

morphogenesis

differentiation

Recognizing meaningful differences

folding · invagination · polarity · segmentation · organizer · condensation

organs

heart

Circulatory system's pump

  • liverAbdominal detoxifying organ
  • kidneyBlood-filtering organ
  • lungRespiratory chest organ

brain · pancreas · intestine · stomach · spleen · thyroid · eye · limb · gonad · tooth

molecular

gene expression

DNA to functional product

ligand · epigenetics · stem cells · growth factors

cellular

apoptosis

Programmed cell death

  • cytoskeletonInternal protein support structure
  • mitosisNuclear division producing identical cells
  • stem cellsUndifferentiated cells with regenerative potential

tissue layers · basement membrane

Opposites
developmental process direction

organogenesisinvolution

Inward-turning process

organ failure · apoptosis · atrophy · necrosis · regression

developmental stage

organogenesiscleavage

Tendency to split cleanly

gastrulation · fertilization · cell division · implantation

biological scale of process

organogenesiscell division

Parent splitting into offspring

cytokinesis · mitosis · cytogenesis

Family

organ, organic, organs, genesis, organism, organisms, organically, organismic, organismal

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