nanopore
Tiny membrane opening
A nanopore is an extremely small hole, typically one to one hundred nanometers in diameter, either occurring naturally in cell membranes or engineered for scientific purposes.
Nanopore technology has revolutionized DNA sequencing by threading genetic material through these tiny openings and reading the sequence as molecules pass through.
Nanopore sequencing can analyze long DNA strands in real time.
The term combines nano-, indicating the billionth-of-a-meter scale, with pore.
Hereditary code molecule
- RNAGene expression molecule
- nucleotideGenetic code subunit
- translocationMovement to another place
- throughputProcessing rate over time
real-time · basepair · strand · adapter · consensus · methylation · cDNA · barcode
Ease of current flow
- currentDirected flow of charge
- signalMessage-conveying cue
- detectionAct of finding something
- blockadeSealing off a place
voltage · electrode · noise · resolution · event · amplitude · threshold · baseline
Thin tissue sheet
- desalinationExtracting salt from seawater
- selectivityTendency to choose carefully
- permeabilityAbility to transmit fluids
- fluxContinuous change or flow
osmosis · separation · fouling · brackish
Passage for transmission
- apertureAdjustable optical inlet
- membraneThin tissue sheet
- solid-stateUsing semiconductors, not tubes
- grapheneMonolayer carbon hexagonal lattice
diameter · angstrom · constriction · vestibule · barrel · lumen · nanofabrication · drilling
Physics applied to life
- electrophysiologyBiology's electrical activity science
- biomoleculeLife-produced chemical compound
- polymerLarge repeated-unit molecule
- proteinFolded amino chain
DNA
Hereditary code molecule
- RNAGene expression molecule
- nucleotideGenetic code subunit
- translocationMovement to another place
throughput · real-time · basepair · strand · adapter · consensus · methylation · cDNA · barcode · multiplexing
conductance
Ease of current flow
blockade · voltage · electrode · noise · resolution · event · amplitude · threshold · baseline · electrolyte
membrane
Thin tissue sheet
- desalinationExtracting salt from seawater
- selectivityTendency to choose carefully
- permeabilityAbility to transmit fluids
flux · osmosis · separation · fouling · brackish
channel
Passage for transmission
- apertureAdjustable optical inlet
- membraneThin tissue sheet
- solid-stateUsing semiconductors, not tubes
graphene · diameter · angstrom · constriction · vestibule · barrel · lumen · nanofabrication · drilling
biophysics
Physics applied to life
- electrophysiologyBiology's electrical activity science
- biomoleculeLife-produced chemical compound
- polymerLarge repeated-unit molecule
protein · polypeptide · biomarker · genomics