ketogenesis
Liver produces ketones
Ketogenesis is the metabolic process by which the liver produces ketones from fatty acids.
This occurs when glucose is scarce—during fasting, prolonged exercise, or carbohydrate restriction.
The ketones serve as alternative fuel for the brain and muscles.
Ketogenic diets deliberately induce this state for weight loss or therapeutic purposes.
Ketone body from fat metabolism
- acetyl-CoAActivated two-carbon metabolic intermediate
- fatty acidsOrganic molecules in fats
- lipolysisMetabolic fat decomposition
- beta-oxidationFatty acid breakdown pathway
mitochondria · carnitine · hepatic · decarboxylation · oxidation · liver · enzymes · NADH
Deliberate food avoidance
- starvationExtreme nutritional deprivation
- glucagonPancreatic blood-sugar raiser
- insulinPancreatic glucose-regulating hormone
- catabolismMetabolic molecular dismantling
Minimal starch intake
- ketoHigh-fat, low-carb regimen
- AtkinsCarbohydrate-restricting eating plan
- macronutrientsPrimary nutritional building blocks
- satietyState of being full
beta-hydroxybutyrate
Ketone body from fat metabolism
- acetyl-CoAActivated two-carbon metabolic intermediate
- fatty acidsOrganic molecules in fats
- lipolysisMetabolic fat decomposition
beta-oxidation · mitochondria · carnitine · hepatic · decarboxylation · oxidation · liver · enzymes · NADH
fasting
Deliberate food avoidance
- starvationExtreme nutritional deprivation
- glucagonPancreatic blood-sugar raiser
- insulinPancreatic glucose-regulating hormone
low-carb
Minimal starch intake
- ketoHigh-fat, low-carb regimen
- AtkinsCarbohydrate-restricting eating plan
- macronutrientsPrimary nutritional building blocks
coma
Unwakeable unconsciousness
- emergencySerious sudden danger
- metabolismcatabolism, anabolism, metabolism, glycolysis, metabolic rate
- Biochemical Pathwaysglycolysis, citric acid cycle, Cori cycle, beta-oxidation, fatty acid synthesis
- biochemistryenzymes, proteins, biochemistry, protein, enzyme
- lipid metabolismlipids, lipogenesis, fats, triglycerides, fat metabolism
- liver functionsdetoxification, drug metabolism, protein synthesis, bile salts, coagulation factors
- amino acidsalanine, arginine, asparagine, cysteine, glutamine
ketogenesisglycolysis
Glucose metabolism producing ATP
lipogenesis · fatty acid synthesis · anabolism · protein synthesis