coagulation factors
Blood-clotting cascade components
Coagulation factors are proteins in blood that work together to form clots.
When tissue is damaged, these factors activate in a cascade—each triggering the next—until fibrin threads form a mesh that stops bleeding.
Hemophilia results from deficiency in specific factors.
Medical contexts number them with Roman numerals: Factor VIII, Factor IX.
Thrombin's inactive precursor
- fibrinogenPlasma protein for coagulation
- thrombinSerine protease enabling coagulation
Protein that hastens reactions
- zymogenInactive enzyme precursor
- cascadeSuccessive downward flow
- activationSetting into operation
- substrateUnderlying supporting material
cofactor · catalyst · kinetics · active site · molecular weight · half-life · biosynthesis
Profuse discharge of blood
- bleeding disorderImpaired blood clotting condition
- prophylaxisPreventive medical treatment
- tranexamic acidClot-stabilizing hemostatic agent
Clot-preventing medication
- heparinSubstance preventing coagulation
- protamine sulfateDrug reversing anticoagulation
prothrombin
Thrombin's inactive precursor
- fibrinogenPlasma protein for coagulation
- thrombinSerine protease enabling coagulation
INR
India's currency code
- D-dimerClot dissolution byproduct
enzyme
Protein that hastens reactions
- zymogenInactive enzyme precursor
- cascadeSuccessive downward flow
- activationSetting into operation
substrate · cofactor · catalyst · kinetics · active site · molecular weight · half-life · biosynthesis
hemorrhage
Profuse discharge of blood
- bleeding disorderImpaired blood clotting condition
- prophylaxisPreventive medical treatment
- tranexamic acidClot-stabilizing hemostatic agent
cross-linking
Bonds joining parallel chains
- extrinsic pathwayCoagulation triggered externally
warfarin
Clot-preventing medication
- heparinSubstance preventing coagulation
- protamine sulfateDrug reversing anticoagulation
- blood testsCBC, blood test, complete blood count, blood work, CMP
- blood clottingfibrin, thrombin, prothrombin, fibrinogen, platelet
- biologicsbiologics, biologicals, biopharmaceuticals, monoclonal antibodies, monoclonal antibody
- Blood Productswhole blood, plasma, platelets, red blood cells, red cells
- blood proteinsalbumin, globulin, globulins, fibrinogen, immunoglobulin
- hemostaticsthrombin, fibrin, platelets, hemostat, tourniquets
coagulation factorsanticoagulants
Clot-preventing medications
heparin · thrombolytics · plasmin · warfarin · blood thinners
factor, factors, coagulate, coagulation, coagulated, anticoagulant, coagulant, coagulating, coagulates