drug metabolism
Liver breaks down pills
Drug metabolism is the body's process of chemically breaking down medications and other foreign substances, primarily in the liver.
Enzymes convert drugs into forms the body can eliminate.
Metabolism affects how long a drug stays active: Her fast drug metabolism means she needs higher doses.
Some drugs are inactive until metabolized into their therapeutic form.
- oxidationLosing electrons chemically
- pharmacokineticsDrug fate in body
- bioavailabilityFraction reaching active circulation
- absorptionProcess of taking in
- liver enzymesProteins catalyzing hepatic reactions
half-life · steady state · reduction · N-acetyltransferase · sulfation · hydrolysis · pharmacogenomics · acetylation · biotransformation · methylation · excretion · deamination · conjugation · clearance · kidneys · blood brain barrier · CYP450 · elimination