immunomodulators

Body's defense tweakers

Immunomodulators are substances that alter the activity of the immune system, either by stimulating it or suppressing it.

They include a wide range of drugs used to treat conditions where the immune system is either underactive (as in some cancers) or overactive (as in autoimmune diseases like rheumatoid arthritis or Crohn's disease).

Her doctor prescribed an immunomodulator to help control the inflammation.

The term encompasses both immunosuppressants, which dampen immune response, and immunostimulants, which enhance it.

agents

biologics

Drugs derived from organisms

glucocorticoids · methotrexate · cyclosporine · thalidomide · interferons

components

cytokines

Immune signaling proteins

T-cells · B-cells · antibodies · macrophages · immunoglobulins · leukocytes · complement proteins · toll-like receptors

treatment

immunotherapy

Disease treatment via body's defenses

adverse effects · dosing · infusion · injection · combination therapy · tapering

mechanisms

signaling

Conveying information nonverbally

enhancement · tolerance · feedback · gene expression · transcription · inflammation · activation · inhibition · cross-talk · cascade

conditions

rheumatoid arthritis

Autoimmune joint disease

lupus · Crohn's disease · ulcerative colitis · transplant rejection · sarcoidosis · vasculitis · scleroderma · Sjögren's syndrome

Opposites
mechanism of action

immunomodulatorsanalgesics

Drugs that reduce pain

painkillers · placebos · antipyretics · antibiotics · bronchodilators

immune effect direction

immunomodulatorsimmunosuppressants

Drugs reducing body defenses

therapeutic specificity

immunomodulatorsbroad-spectrum antibiotics

Drugs killing varied bacteria

general anesthetics

Family

immune, immunity, modulate, modulation, modular, immunization, autoimmune, modulator, immunology

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