chondrocyte
Cell in cartilage
A chondrocyte is a cell found in cartilage, responsible for producing and maintaining the cartilage matrix.
These cells sit in small cavities called lacunae and secrete the collagen and proteoglycans that give cartilage its resilient, flexible structure.
Damaged chondrocytes can lead to joint degeneration.
Glassy, translucent substance
- fibrocartilageDense, collagen-rich connective tissue
- elasticAble to stretch, rebounds
- matrixOrdered numerical arrangement
- collagenStructural body protein
synovial · meniscus · intervertebral · trachea · auricular · nasal · costal · ossification
Restore to working order
- healingRestoration of health
- transplantationSurgical organ relocation
- implantationEmbedding into tissue
- autologousFrom the same organism
scaffold · hydrogel · culture · expansion · pellet · graft · resurfacing
Cartilage breakdown in joints
- degradationDecline in condition
- degenerationProgressive loss of function
- inflammationProtective tissue response
- apoptosisProgrammed cell death
senescence · catabolic · rheumatoid · erosion · fibrillation · calcification · necrosis · dysfunction
Bone-forming cell
- fibroblastFiber-producing connective cell
- periosteumFibrous bone covering
- cytoskeletonInternal protein support structure
- extracellularOutside the cell membrane
autophagy · apoptosis · senescence · metabolism · phenotype · morphology
Ancestor or originator
- proliferationRapid increase in quantity
- maturationProcess of becoming complete
- hypertrophyTissue enlargement via cells
- terminalAt the endpoint
commitment · lineage · condensation · signaling · pathway · transcription
hyaline
Glassy, translucent substance
- fibrocartilageDense, collagen-rich connective tissue
- elasticAble to stretch, rebounds
- matrixOrdered numerical arrangement
collagen · synovial · meniscus · intervertebral · trachea · auricular · nasal · costal · ossification · lacuna
repair
Restore to working order
- healingRestoration of health
- transplantationSurgical organ relocation
- implantationEmbedding into tissue
autologous · scaffold · hydrogel · culture · expansion · pellet · graft · resurfacing
osteoarthritis
Cartilage breakdown in joints
- degradationDecline in condition
- degenerationProgressive loss of function
- inflammationProtective tissue response
apoptosis · senescence · catabolic · rheumatoid · erosion · fibrillation · calcification · necrosis · dysfunction · damage
osteoblast
Bone-forming cell
- fibroblastFiber-producing connective cell
- periosteumFibrous bone covering
- cytoskeletonInternal protein support structure
extracellular · autophagy · apoptosis · senescence · metabolism · phenotype · morphology
progenitor
Ancestor or originator
- proliferationRapid increase in quantity
- maturationProcess of becoming complete
- hypertrophyTissue enlargement via cells
terminal · commitment · lineage · condensation · signaling · pathway · transcription