aquaporin

Membrane water channel

Aquaporins are proteins embedded in cell membranes that form channels allowing water molecules to pass rapidly in and out of cells.

These molecular gatekeepers are found throughout living organisms, from bacteria to humans, and play crucial roles in processes like kidney filtration, plant water uptake, and tear production.

Scientists sometimes call them "water channels" for their specialized function of facilitating osmotic flow while blocking ions and other solutes.

function

water transport

Movement via waterways

homeostasis · single-file · water balance · reabsorption · secretion · gating · regulation · trafficking

biochemistry

protein

Folded amino chain

gene expression · synthesis · phosphorylation · vasopressin · localization · knockout · molecular weight · purification · crystallography · mutagenesis

physiology

kidney

Blood-filtering organ

lung · salivary gland · edema · glaucoma · nephron · sweat gland · epithelium · endothelium · astrocyte · choroid plexus

structure

channel

Passage for transmission

constriction · vestibule · monomer · narrowing · angstrom

research

Nobel Prize

Highest academic honor

inhibitor · mercury · biomarker · gene therapy · membrane protein · discovery · characterization

Opposites
channel selectivity

aquaporinsodium channel

Protein allowing sodium passage

chloride channel

Family

aquaporins

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