Huntington's
Inherited brain disorder
Huntington's is short for Huntington's disease, a hereditary neurological disorder causing progressive deterioration of mental and physical abilities.
Symptoms typically appear in middle age and include involuntary movements, cognitive decline, and psychiatric disturbances.
The disease is fatal, usually within fifteen to twenty years of onset.
She tested positive for the Huntington's gene.
Involuntary jerking muscle disorder
- movement disorderNeurological motor dysfunction
- cognitive declineWorsening of thought abilities
- dementiaChronic cognitive impairment
- basal gangliaSubcortical motor-control nuclei
striatum · neurodegeneration · involuntary movements · dysarthria · dysphagia · bradykinesia · rigidity · neurons
Permanent DNA alteration
- chromosomeDNA strand carrying genes
- geneHereditary information unit
- dominantHaving superior influence
- penetranceGenotype-to-phenotype expression ratio
DNA · allele · genotype · sequencing · genome · nucleotide · transcription · expressivity
Property received from ancestors
- family historyRecord of ancestors
- pedigreeRecord of descent
- genealogyStudy of family descent
- ancestryFamily line of descent
lineage · heredity · offspring · descendants · progeny · at-risk · parent · transmission
Identification of illness
- prognosisPredicted disease course
- onsetStarting point of something
- progressionSequential forward movement
- juvenileYoung person or animal
late-stage · symptoms · psychiatrist · neurologist · care team · palliative · supportive care · clinical trial
chorea
Involuntary jerking muscle disorder
- movement disorderNeurological motor dysfunction
- cognitive declineWorsening of thought abilities
- dementiaChronic cognitive impairment
basal ganglia · striatum · neurodegeneration · involuntary movements · dysarthria · dysphagia · bradykinesia · rigidity · neurons · Woody Guthrie
mutation
Permanent DNA alteration
- chromosomeDNA strand carrying genes
- geneHereditary information unit
- dominantHaving superior influence
penetrance · DNA · allele · genotype · sequencing · genome · nucleotide · transcription · expressivity · locus
inheritance
Property received from ancestors
- family historyRecord of ancestors
- pedigreeRecord of descent
- genealogyStudy of family descent
ancestry · lineage · heredity · offspring · descendants · progeny · at-risk · parent · transmission · genetic counseling
diagnosis
Identification of illness
- prognosisPredicted disease course
- onsetStarting point of something
- progressionSequential forward movement
juvenile · late-stage · symptoms · psychiatrist · neurologist · care team · palliative · supportive care · clinical trial · biomarker
- chronic conditionsdiabetes, heart disease, asthma, arthritis, hypertension
- Medical EponymsAlzheimer's, Parkinson's, Crohn's disease, Down syndrome, Bell's palsy
- Brain Disordersdementia, Alzheimer's, epilepsy, Parkinson's, Alzheimer's disease
- Genetic Conditionscystic fibrosis, sickle cell, hemophilia, muscular dystrophy, Down syndrome
- Genetic Disorderscystic fibrosis, hemophilia, sickle cell disease, sickle cell anemia, sickle cell
- Neurodisabilitiescerebral palsy, autism, epilepsy, ASD, ADHD
Huntington'sinfectious disease
Pathogen-caused transmissible ailment
traumatic brain injury · meningitis · encephalitis · stroke · mad cow disease
Huntington'sbenign tumor
Harmless abnormal growth
bacterial meningitis · bacterial infection · appendicitis · strep throat · broken bone
- Huntington's diseaseInherited fatal neurodegenerative condition