osteonecrosis
Dead bone tissue
Osteonecrosis is the death of bone tissue due to insufficient blood supply.
Without adequate circulation, bone cells die and the affected area may eventually collapse.
The condition most commonly affects the hip, knee, and shoulder joints: The patient developed osteonecrosis after prolonged steroid use.
Also called avascular necrosis.
Inflammation-suppressing steroid medications
- alcohol useConsuming intoxicating beverages
- chemotherapyAnti-cancer drug treatment
- radiation therapyIonizing beams treating malignancies
- organ transplantMoving tissue between bodies
lupus · rheumatoid arthritis · HIV · hyperlipidemia · trauma · fracture · dislocation · immunosuppression
Circulatory delivery to tissues
- hypoxiaInsufficient tissue oxygenation
- thrombosisClot forming in vessel
- embolismObstruction in blood vessel
- anoxiaAbsence of oxygen supply
hypoperfusion · perfusion · atherosclerosis · vasoconstriction · sickle cell · decompression sickness · clotting
Ache at skeletal junctures
- stiffnessResistance to deformation
- tendernessGentle, caring quality
- hip painDiscomfort at pelvis joint
- knee painDiscomfort in leg joint
shoulder pain · limp · swelling · crepitus · referred pain · muscle weakness · gait disturbance · instability
Magnetic body imaging
Transplanted skeletal tissue
- joint replacementImplanting artificial articulation
- anticoagulantsClot-preventing medications
- stem cell therapyTreatment using primordial cells
- electrical stimulationCurrent applied to body
corticosteroids
Inflammation-suppressing steroid medications
- alcohol useConsuming intoxicating beverages
- chemotherapyAnti-cancer drug treatment
- radiation therapyIonizing beams treating malignancies
organ transplant · lupus · rheumatoid arthritis · HIV · hyperlipidemia · trauma · fracture · dislocation · immunosuppression
blood supply
Circulatory delivery to tissues
- hypoxiaInsufficient tissue oxygenation
- thrombosisClot forming in vessel
- embolismObstruction in blood vessel
anoxia · hypoperfusion · perfusion · atherosclerosis · vasoconstriction · sickle cell · decompression sickness · clotting
joint pain
Ache at skeletal junctures
- stiffnessResistance to deformation
- tendernessGentle, caring quality
- hip painDiscomfort at pelvis joint
knee pain · shoulder pain · limp · swelling · crepitus · referred pain · muscle weakness · gait disturbance · instability · clicking
MRI
Magnetic body imaging
bone graft
Transplanted skeletal tissue
- joint replacementImplanting artificial articulation
- anticoagulantsClot-preventing medications
- stem cell therapyTreatment using primordial cells
electrical stimulation · non-weight-bearing · NSAIDs · physical therapy
necrosis, osteoporosis, necrotic, osteopathy, osteoblast, osteocyte, necroses, necrose, necrotizing