lipoprotein lipase
Triglyceride-splitting protein
Lipoprotein lipase is an enzyme that breaks down triglycerides in lipoproteins—the particles that transport fats through the bloodstream.
Found on the walls of blood vessels, it releases fatty acids from circulating lipoproteins so tissues can absorb them for energy or storage.
Deficiency causes severely elevated blood fats: Lipoprotein lipase deficiency can lead to dangerous triglyceride levels.
Three-chained fat molecules
- hydrolysisWater-induced bond cleavage
- fatty acidsOrganic molecules in fats
- glycerolTrihydric alcohol, viscous, sweet
- HDLBeneficial blood lipid
LDL · lipolysis · cofactor · catalysis · endothelium · capillary · phospholipids · cholesterol
Capturing power for later
- insulinPancreatic glucose-regulating hormone
- glucagonPancreatic blood-sugar raiser
- adipocytesLipid-storing cells
- lipogenesisMetabolic fat production process
ketogenesis · nutrient absorption · muscle tissue · postprandial · fasting · obesity · metabolic syndrome · caloric intake
Lack of something needed
- pancreatitisSwollen digestive gland
- atherosclerosisArterial plaque accumulation disease
- cardiovascular diseaseAilment of circulatory organs
- diagnosisIdentification of illness
Permanent DNA alteration
- polymorphismMany forms, one interface
- alleleGene variant at one locus
- genotypeOrganism's complete allele set
- phenotypeObservable characteristics of organism
inheritance · locus · sequencing · transcription · translation · recessive · dominant · heredity
triglycerides
Three-chained fat molecules
- hydrolysisWater-induced bond cleavage
- fatty acidsOrganic molecules in fats
- glycerolTrihydric alcohol, viscous, sweet
HDL · LDL · lipolysis · cofactor · catalysis · endothelium · capillary · phospholipids · cholesterol · adipocytes
energy storage
Capturing power for later
- insulinPancreatic glucose-regulating hormone
- glucagonPancreatic blood-sugar raiser
- adipocytesLipid-storing cells
lipogenesis · ketogenesis · nutrient absorption · muscle tissue · postprandial · fasting · obesity · metabolic syndrome · caloric intake · weight management
deficiency
Lack of something needed
- pancreatitisSwollen digestive gland
- atherosclerosisArterial plaque accumulation disease
- cardiovascular diseaseAilment of circulatory organs
diagnosis · therapy · gene therapy · dietary restriction · statins
mutation
Permanent DNA alteration
- polymorphismMany forms, one interface
- alleleGene variant at one locus
- genotypeOrganism's complete allele set
phenotype · inheritance · locus · sequencing · transcription · translation · recessive · dominant · heredity · genetic testing
- lipid enzymesHMG-CoA reductase
- Blood Lipidscholesterol, LDL, HDL, triglycerides, total cholesterol
- enzymesamylase, protease, kinase, enzyme, enzymes