lethal dose

Kills if taken

A lethal dose is the amount of a substance—drug, poison, radiation—sufficient to cause death.

In pharmacology and toxicology, LD50 designates the dose lethal to fifty percent of test subjects, a standard measure of toxicity.

The term appears in medical contexts, murder investigations, and discussions of overdose: The coroner determined she had ingested a lethal dose of barbiturates.

fatal

mortality

State of eventual death

kill · perish · demise · extinction · annihilation · doom · casualty · victim · coroner · autopsy

threshold

LD50

Half-fatal dose measurement

margin of safety · bioavailability · accumulation · body weight · susceptibility

poison

arsenic

Toxic metalloid element

  • cyanideToxic carbon-nitrogen compound
  • venomInjected animal poison
  • ricinToxic castor compound

strychnine · belladonna · hemlock · curare · botulinum · neurotoxin · anthrax · polonium · thallium · paraquat

substance

radiation

Energy propagation through space

methanol · antifreeze · digitalis · potassium chloride · insulin · acetaminophen · aspirin · caffeine · nicotine · water intoxication

overdose

overmedication

Excessive pharmaceutical treatment

barbiturate · sedative · narcotic · suicide · self-harm · emergency · naloxone · activated charcoal · toxicology screen

Categories
Opposites
biological effect

lethal dosesafe dose

Amount causing no harm

microdose · low dose · micro-dose

HARM vs. BENEFIT

lethal dosetherapeutic dose

Drug amount that heals

maintenance dose · recommended dose · remedy

safety/danger threshold

lethal dosesafe dose

Amount causing no harm

permissible dose · safety margin · recommended dose

Family

dose, lethal, overdose, dosed, dosage, dosing, lethality, overdoses, lethally

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